Cureus
Cure8 research brief
Why This Matters
MMF-associated enterocolitis can look like other serious causes of colitis and may be underrecognized in lung transplant patients. Correctly identifying MAE can avoid misdiagnosis and inappropriate treatments.
Who Should Pay Attention
Clinicians caring for transplant recipients, gastroenterologists, pathologists, and lung transplant patients who take mycophenolate mofetil.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This abstract reports a case-series analysis of 12 lung transplant patients with suspected MMF-associated enterocolitis (MAE). Symptoms reported include diarrhea, nausea, vomiting, and occasional bleeding.
Endoscopic appearance ranged from normal to erythema and ulcers, and biopsy features overlapped with GVHD, CMV colitis, ischemic colitis, and IBD, making diagnosis difficult.
Clinicians should consider MAE in transplant recipients on MMF who develop new GI symptoms, and correlation of clinical history, medication exposure, targeted infectious testing (for CMV), and cautious pathology review are needed to avoid misdiagnosis.
Keep In Mind
Abstract-only source and small sample size (12 patients) limit generalizability. The report is descriptive and focuses on diagnostic recognition rather than treatment trials or outcomes.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationCureus
AuthorsShen L, Wang Y, Kontosis A +3 more
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedSep 15, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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