Keep up with the latest Crohn's and UC developments.
an investigational oral drug (PALI-2108) being developed specifically for UC and Crohn’s disease, reporting favorable Phase 1 safety and early activity and noting upcoming Phase 2 readouts. For people following new...
Find updates by what you are tracking.
This trial directly tests common clinical strategies for managing loss of response to ustekinumab in Crohn’s disease. The findings may change whether doctors routinely escalate to 4-weekly dosing after an IV reinduction,...
Many people with Crohn's also have obesity or diabetes and may be prescribed GLP-1 drugs. Understanding safety, symptom overlap, and current research helps you and your care team make informed choices about starting or...
New approvals and pipeline activity can expand future treatment options and affect availability, pricing, and research priorities for Crohn’s disease. Market analyses can signal which therapies companies expect to...
This study suggests a targeted phage can reduce inflammation driven by Crohn’s‑associated E. coli without wiping out the gut microbiome, and it may boost the effect of lower steroid doses. That could eventually mean...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease, Crohn's disease, and Irritable bowel syndrome. The original article is from msn.com.
This study quantifies the large NHS and societal costs of Crohn’s disease and ulcerative colitis in the UK and highlights that ongoing management and maintaining remission are major drivers of expense.
This study suggests a new, targeted way to reduce gut inflammation by disabling harmful E. coli behaviors linked to Crohn's disease without wiping out the microbiome.
Based on the title and source metadata, this appears to be a basic science related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from msn.com.
Cure8 found this source from academic.oup.com, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease, Crohn's disease, and Research and clinical trials. Open the original article for...
If correct, the paper points to a previously underappreciated immune cell (GzmK+ tissue-resident CD8+ T cells) as a potential driver of Crohn’s inflammation — which could lead to new biomarkers or therapies that work...
Based on the title and source metadata, this appears to be a patient story related to Crohn's disease and Procedures and surgery. The original article is from msn.com.
Based on the title and source metadata, this appears to be a patient story related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from msn.com.
The story shows that emergency surgery and coordinated specialist care can treat life‑threatening Crohn’s complications and help patients regain daily activities. It highlights the role of reconstructive surgery and...
Growth and nutrition are major concerns in children with Crohn’s disease. This study suggests perianal disease and common inflammatory and nutritional markers may help predict which children are at higher risk for...
This story shows how untreated or undiagnosed Crohn’s symptoms — especially perianal disease and an abdominal abscess — can become life-threatening. It underscores the importance of seeking medical attention for...
Genetic studies help reveal biological pathways behind Crohn’s disease, which can guide research into new treatments and better understanding of disease mechanisms. People with Crohn’s disease may find it useful to know...
Cure8 found this source from mshale.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness. Open the original article for the full...
The study pinpoints a genetic cause (BIRC3 variants) that disrupts a TNF/RIPK1 immune pathway linked to Crohn’s disease, suggesting a targetable mechanism. That could help doctors match patients to treatments and guide...
Diet-based induction options matter for children because EEN can be hard to tolerate. This study finds CDED (with partial enteral nutrition) performs similarly to EEN for inducing remission and mucosal healing in...
Fibrostenotic Crohn’s disease causes strictures and often requires surgery; emerging anti‑fibrotic therapies aim to prevent or slow structural bowel damage beyond inflammation control. Patients and clinicians may see new...
Noninvasive tests at 3 months after ileocecal resection (ultrasound + fecal calprotectin) may identify patients at high risk of endoscopic recurrence by 6 months. That could help avoid or target postoperative endoscopy...
Cure8 could only read part of this source from law360.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease and Access, cost, and policy.
Terminal ileitis affects the terminal ileum and is most commonly linked to Crohn’s disease, so people with IBD or abdominal symptoms should know it can cause pain, diarrhea, and, in some cases, serious complications.
This article shares a personal, nonmedical perspective promoting lifestyle, faith, and avoiding biologic drugs. Patients with Crohn’s may encounter similar messages and should know this represents one person’s experience...
Based on the title and source metadata, this appears to be an event or fundraiser related to Crohn's disease and Community and awareness. The original article is from msn.com.
Cure8 found this source from iovs.arvojournals.org, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Biomarker. Open the original article for the full...
This study suggests a biological link between NOD2 gene dysfunction and estrogen signaling that could help explain why Crohn’s disease is more common in females and point to a new, hormone-related pathway to investigate...
Scientists found BIRC3 gene changes that cause Crohn’s in some patients and showed those changes drive inflammation through the RIPK1/TNF pathway. That suggests a new, druggable pathway and may help predict who benefits...
This study identifies a specific genetic cause (BIRC3 variants) that drives inflammation through the RIPK1/TNF pathway and points to an existing drug target (RIPK1). If validated, the finding could help match patients to...
This trial targets fibrotic narrowings (strictures) in Crohn’s disease — a common complication without approved drug treatments — so positive results could change care options and reduce the need for surgery.
People with Crohn’s disease and their families may relate to the caregiving, hospital stays, and the need for community support when managing complex chronic illness. The story highlights practical and emotional burdens...
Cure8 could only read part of this source from gurufocus.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease and Research and clinical trials.
Many people with Crohn’s use social media for information; this study shows popular Instagram Reels are only moderate in quality and can contain misinformation regardless of who posts them. That means patients should be...
Many people with Crohn’s and IBD turn to Instagram Reels for information. This study found that a lot of that content is only moderate in quality and some contains clinically significant misinformation, which could...
Cure8 found this source from youtube.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Other Autoimmune Disease, and Community and awareness. Open the original article for the full...
This large real-world study suggests GLP-1 receptor agonists used in adults with Crohn’s disease and obesity were associated with lower healthcare use and lower subsequent TNF inhibitor use at 1 and 5 years, findings...
This study reports real-world effectiveness of risankizumab for refractory Crohn's disease, showing many patients achieved steroid-free remission. The results are relevant for people weighing treatment options after...
Cure8 found this source from marketscreener.com, but the page could not be read reliably yet. It is tagged for Crohn's disease and Research and clinical trials. Open the original article for the full details.
Many people with IBD avoid NSAIDs because of flare concerns. This large study suggests prescription NSAIDs did not meaningfully increase hospitalization risk overall, but patients with Crohn disease showed a higher risk....
This study suggests risankizumab may improve quality of life and reduce common symptoms (fatigue, mood, urgency) more than ustekinumab for patients with moderate-to-severe Crohn’s disease who didn’t respond to anti-TNF...
Cure8 could only read part of this source from eurekalert.org, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness.
Many people with Crohn’s look to short social videos for information. Moderate-quality and misleading reels could influence treatment decisions, emotional wellbeing, and when people seek medical care.
People with Crohn’s disease often seek information and support on social media; this study shows Instagram Reels vary in quality and medical-advice videos may include misinformation. That matters because inaccurate...
Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from msn.com.
A reliable, accurate intestinal ultrasound could make routine monitoring easier, faster, and less costly than repeated MRI for people with Crohn’s disease. The study shows strong agreement between ultrasound scores and...
There are many new drugs and trials underway for Crohn’s disease, which could expand future treatment options. Recent phase 2 and phase 3 starts from major pharma show active investment in IBD research.
Researchers mapped cell-type gene activity in Crohn’s ileum and found persistent immune-related gene activation in stem cells after inflammation healed, plus macrophage signatures tied to the JAK/STAT pathway. This could...
