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Inflammatory bowel disease-rheumatology: evaluation of a collaborative, multidisciplinary, patient-centred care model
Frontline Gastroenterology

Inflammatory bowel disease-rheumatology: evaluation of a collaborative, multidisciplinary, patient-centred care model

Many people with IBD also have inflammatory joint disease. This combined clinic model aimed to provide simultaneous gastroenterology and rheumatology assessment and shared decision-making, and the study reports frequent...

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Pitfalls in the Diagnosis and Classification of Crohn's Disease: Misdiagnosis, Overdiagnosis, and Misclassification.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

Pitfalls in the Diagnosis and Classification of Crohn's Disease: Misdiagnosis, Overdiagnosis, and Misclassification.

Accurate diagnosis and classification affect treatment choices and risks—misdiagnosis can lead to unnecessary immunosuppression, while misclassification can under-recognize severe or proximal disease that needs different...

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Validation and Reliability of the Turkish Version of the Inflammatory Bowel Disease-Disk in Patients with Inflammatory Bowel Disease.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

Validation and Reliability of the Turkish Version of the Inflammatory Bowel Disease-Disk in Patients with Inflammatory Bowel Disease.

Validated patient-reported measures help track how IBD affects daily function and well-being. A Turkish IBD-Disk gives clinicians and researchers a standardized way to measure patient-perceived disease burden and monitor...

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Baseline mucosal transcriptomic endotypes stratify healing capacity and biologic therapy outcomes in ulcerative colitis: an integrative multi-cohort study
Frontiers in Pharmacology

Baseline mucosal transcriptomic endotypes stratify healing capacity and biologic therapy outcomes in ulcerative colitis: an integrative multi-cohort study

If baseline mucosal gene-expression patterns can identify patients more likely to achieve mucosal healing across drug classes, those patterns could eventually help personalize treatment selection or stratify patients in...

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Reviewer #1 (Public review): GM-CSF regulates conserved ILC-like transcriptional states and myeloid cell signaling during ulceration in Crohn’s disease
eLife Sciences Publications, Ltd

Reviewer #1 (Public review): GM-CSF regulates conserved ILC-like transcriptional states and myeloid cell signaling during ulceration in Crohn’s disease

The review evaluates a revised preprint linking GM-CSF, macrophages, and ILC-like cells in Crohn’s disease using human spatial transcriptomics and zebrafish experiments. It highlights limitations that matter because they...

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Knowledge, Attitude, and Practice in Inflammatory Bowel Disease: Associated Factors and the Mediating Role of Attitude.
Patient preference and adherence

Knowledge, Attitude, and Practice in Inflammatory Bowel Disease: Associated Factors and the Mediating Role of Attitude.

Self-management is central to long-term IBD control. The study shows many patients have limited disease knowledge and less favorable attitudes, which could affect adherence, lifestyle choices, and follow-up.

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A Comprehensive Ayurvedic Appraisement of Ulcerative Colitis: Pathophysiological Correlations and Management Strategies Via Purishavaha Sroto Dushti and Grahani Roga
International Journal of Innovative Science and Research Technology

A Comprehensive Ayurvedic Appraisement of Ulcerative Colitis: Pathophysiological Correlations and Management Strategies Via Purishavaha Sroto Dushti and Grahani Roga

The article offers an Ayurvedic framework for understanding and managing ulcerative colitis that may interest patients seeking complementary approaches and clinicians exploring integrative care. It emphasizes dietary and...

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Determination of the approach of Polish gastroenterologists and surgeons to the diagnosis and treatment of complex cases of Crohn's disease-related perianal fistulas.
Przeglad gastroenterologiczny

Determination of the approach of Polish gastroenterologists and surgeons to the diagnosis and treatment of complex cases of Crohn's disease-related perianal fistulas.

Perianal fistulas are a common, challenging Crohn's complication that often need combined medical and surgical care; understanding local practice patterns helps patients and clinicians anticipate typical treatments and...

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Separating Prognostic Association from Treatment-Effect Modification of a Baseline Mucosal Inflammatory-Response Score in Ulcerative Colitis Biologic Trials.
Clinics and research in hepatology and gastroenterology

Separating Prognostic Association from Treatment-Effect Modification of a Baseline Mucosal Inflammatory-Response Score in Ulcerative Colitis Biologic Trials.

Researchers and clinicians want biomarkers that predict outcome or tailor treatment. This study suggests a mucosal gene-expression score is prognostic and declines in responders, but it does not yet show the score...

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Fatigue across physical and mental health conditions: results from a multicenter study at the German Center for Mental Health.
Journal of psychosomatic research

Fatigue across physical and mental health conditions: results from a multicenter study at the German Center for Mental Health.

The study directly compares fatigue levels across several chronic conditions using the same validated tools, offering context for how fatigue in IBD compares to other illnesses. That context can help patients and...

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Gut Microbiota-Driven Neuroimmune Crosstalk in Ulcerative Colitis: From Mechanisms to Therapeutic Implications
Biomedicines

Gut Microbiota-Driven Neuroimmune Crosstalk in Ulcerative Colitis: From Mechanisms to Therapeutic Implications

Understanding microbiota–neuroimmune interactions could explain why symptoms like urgency and pain persist in some people with UC and may point to new treatment strategies that go beyond conventional anti-inflammatory...

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Ulcerative colitis, but not Crohn's disease, displays demographically and clinically driven mucosal immune heterogeneity: implications for patient stratification.
Frontiers in immunology

Ulcerative colitis, but not Crohn's disease, displays demographically and clinically driven mucosal immune heterogeneity: implications for patient stratification.

The findings suggest that tissue-based immune profiling may better identify biologically distinct subgroups in ulcerative colitis than blood tests, which could affect research on personalized treatment or trial...

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