Condition
Colorectal cancer news when it appears alongside Crohn's disease, ulcerative colitis, IBD risk, screening, or surveillance.
41 articles
Colon-targeted delivery systems aim to concentrate drugs in the colon, which could improve effectiveness and reduce systemic side effects for IBD and colorectal cancer treatments. Understanding these approaches helps...
The study links activation of the cGAS–STING immune-sensing pathway to NF-κB–driven inflammation and tumor formation in UC models, which could help explain mechanisms behind colitis-associated colorectal cancer risk.
This model could improve how researchers study IBD inflammation and early colorectal cancer in a human-derived, multicellular system that reproduces neuromuscular function and immune responses. That may speed preclinical...
LRMDA may be a previously unrecognized protein important for mucus production and intestinal barrier integrity — processes directly relevant to IBD flares, infection risk, and colorectal cancer development. Understanding...
The study introduces a phylogeny-aware AI method that may improve detection and interpretation of microbiome signatures linked to IBD and colorectal cancer, which could help research into microbial biomarkers relevant to...
People with ulcerative colitis face a higher colorectal cancer risk driven in part by chronic inflammation; this review explains the molecular and immune mechanisms behind that risk and highlights biomarkers and...
New high-resolution, multilayer imaging tools can reveal how immune cells, epithelium, and enteric nerves interact in the intestine—processes central to IBD, colorectal cancer risk, and gut-brain disorders.
The study reports a targeted nanoparticle designed to deliver celastrol selectively to inflamed intestinal tissue and colorectal tumors, which could—if translated successfully—address limitations of oral celastrol and...
Better triage methods that combine FIT with demographics and blood biomarkers could reduce unnecessary colonoscopies while keeping sensitivity for colorectal cancer and other serious findings, which matters for...
Smoking-related products may influence Crohn’s disease recurrence after surgery; patients and clinicians may want to be aware of new data comparing heat-not-burn tobacco and e-cigarette use to nonsmoking after ileocolic...
Dysplasia is the key premalignant change that raises colorectal cancer risk in people with colonic IBD. Better detection and clearer management pathways can reduce cancer risk and help patients avoid unnecessary surgery.
Researchers and clinicians are exploring how fucose metabolism affects gut barrier function, immunity, and microbiota — processes central to IBD and colorectal cancer. If validated, fucosylation biomarkers or treatments...
Researchers and clinicians looking for blood- or tissue-based molecular tests for IBD may find these integrated transcriptomic analyses useful because they identify candidate diagnostic biomarkers and highlight shared...
Early, noninvasive biomarkers could help detect ulcerative colitis and related colorectal cancer risk sooner. This study identifies four serum-accessible proteins with promising diagnostic accuracy in the reported...
This study helps distinguish patterns of colorectal dysplasia seen in people without IBD from those seen in IBD, which may affect how pathologists and clinicians interpret biopsy findings and consider cancer risk and...
This study could validate a noninvasive stool-test strategy (FIT + fecal calprotectin) to triage which long-standing UC patients need colonoscopy, potentially improving surveillance efficiency and adherence.
The PD‑1/PD‑L1 pathway helps suppress harmful inflammation in IBD but can later allow colorectal tumors to avoid immune attack; understanding this balance matters for patients concerned about long‑term cancer risk and...
IBD and other lower-GI disorders may benefit from oral hydrogel platforms that improve local drug delivery while deliberately engaging the gut microbiota. Understanding this research direction helps patients and...
Shows which IBD comorbidities may be driven in part by shared inherited genetic risk and which likely reflect non-genetic factors, information that could shape future risk stratification and screening approaches for...
The review connects molecular cell-cycle changes to the progression from chronic IBD to colorectal cancer, pointing to pathways and cell-cycle regulators that could become prevention or treatment targets for...
The paper identifies Siglec‑E as an immune brake that limits colitis severity and colitis‑associated tumor development in mice, connecting an immune‑regulatory pathway to inflammation‑driven colorectal cancer risk—an...
The paper identifies a biologic pathway that links epithelial AhR signaling to NK cell–mediated tumor surveillance in the colon. For people with IBD, mechanisms that increase immune escape could relate to...
Based on the title and source metadata, this appears to be a regulatory update related to Colorectal cancer, Blood Test, and Tests and monitoring. The original article is from hmpgloballearningnetwork.com.
The study suggests a cellular redox pathway (selenium vs thiol axis) that is altered differently in Crohn's disease versus colorectal cancer, which could point to disease vulnerabilities and possible links to treatment...
Researchers are investigating RBM47 because it influences RNA processing and immune pathways that could modify inflammation and disease processes relevant to IBD. If borne out, RBM47 could become a biomarker or...
Based on the title and source metadata, this appears to be a case report related to Ulcerative colitis, Colorectal cancer, and Procedures and surgery. The original article is from Gastroenterology report.
The study will prospectively evaluate how often dysplasia occurs, how lesions look and behave after endoscopic resection, and what factors predict local or distant recurrence—information that could change surveillance...
This study highlights factors—tumor location, age, smoking, and having IBD—that were associated with survival and progression in a Lebanese CRC cohort.
Cure8 indexed source-provided abstract text from OpenAlex, but this record did not meet the threshold for a full Cure8 brief. It is tagged for Colorectal cancer, Inflammatory bowel disease, and Complications.
New or improved fluorescent probes could enable more sensitive, noninvasive imaging of biochemical changes in the gut, which may aid research, earlier diagnosis, or monitoring of IBD and colorectal cancer.
Based on the title and source metadata, this appears to be a basic science related to Inflammatory bowel disease, Colorectal cancer, and Research and clinical trials. The original article is from Cell Cycle.
This review collects preclinical evidence that a traditional Chinese medicine formula (Gegen Qinlian Decoction) may act on inflammation, the gut barrier, immunity, and microbiota — all relevant to ulcerative colitis and...
Nanoparticle technologies could eventually enable more targeted drug delivery and improved imaging for IBD and related GI diseases, which may lead to better diagnosis and less systemic side effects. However, translation...
People with long-standing ulcerative colitis face an increased risk of colorectal cancer; this study highlights PPARGC1A as a gene that may be downregulated early in that progression, which could eventually help identify...
People with longstanding ulcerative colitis face higher colorectal cancer risk; this project focuses on a specific immune/stromal cell population (ST2+ cells responding to IL-33) that may help explain how chronic...
People with Crohn’s often have other inflammatory or immune-related conditions. Knowing these links can help patients and clinicians watch for symptoms that might need evaluation or treatment.
Chronic inflammation in Crohn’s, especially when the colon is affected, raises colorectal cancer risk over time. Knowing risk factors and recommended screening helps people with Crohn’s get earlier detection and...
If you have IBD or are at risk for colorectal disease, clinicians at the conference highlighted that these conditions are being seen more often and that treatment approaches have shifted toward personalized medicine and...
The article reports rising colorectal disease and IBD rates and describes modern shifts in treatment—topics that can affect screening, treatment options, and specialist care access for people with IBD or colorectal...
Based on the title and source metadata, this appears to be a biomarker study related to Colorectal cancer and Tests and monitoring. The original article is from msn.com.
People with celiac disease may have higher risks for several digestive cancers and for inflammatory bowel diseases (Crohn’s and UC) according to this large French cohort study. Knowing these associations can help...
