Condition
Colorectal cancer news when it appears alongside Crohn's disease, ulcerative colitis, IBD risk, screening, or surveillance.
Page 1 of 2 · 75 articles
If oral microbes can influence the gut, that could open new ways to monitor or modify disease activity in IBD (for example saliva-based biomarkers or oral-targeted interventions). It also highlights modifiable factors...
A positive stool screening test requires diagnostic colonoscopy to check for colorectal cancer or other treatable conditions. Understanding why some people skip follow-up helps programs reduce missed diagnoses and...
A reusable transcriptomic atlas could let researchers compare new IBD biopsy datasets to a common reference, improving cross-study comparisons and helping separate inflammation from persistent disease-state biology that...
A simple, low-cost fecal blood assay for mice can speed and lower the cost of preclinical studies of colorectal cancer and GI diseases. For IBD/Crohn’s research, it offers a way to monitor intestinal bleeding and link it...
Stories like this highlight the importance of cancer screening and paying attention to symptoms — especially when there’s a family history of bowel disease — and show how diagnosis and treatment affect families...
Food insecurity was linked with higher odds of having IBD and other GI conditions in a large U.S. survey, and many affected people lacked benefits or cancer screening. This matters because access to sufficient nutritious...
Engineered extracellular vesicles are an emerging, targeted therapy approach that could someday improve immune control, mucosal healing, and drug delivery in IBD and reduce colitis-associated cancer risk. The review...
The review links TCM-derived compounds to mechanisms (microbiota, metabolites, immunity) that are implicated in progression from chronic colitis to colorectal cancer, which is an important long-term risk for people with...
Crohn's is becoming more common among younger Americans and long-term uncontrolled inflammation raises colorectal cancer risk. Understanding possible lifestyle and medical factors can help patients and clinicians focus...
A dedicated Digestive Health Centre could make it easier for people with IBD (including children and teens) to access coordinated care—fewer separate visits and more centralized specialist services in one location.
Researchers are studying how gut bacteria evade therapeutic phages, which could affect development of phage-based treatments for drug-resistant infections and potentially influence understanding of bacteria linked to IBD...
This study maps a shared transcriptional programme linking inflamed IBD tissue to colorectal cancer pathways, highlighting potential biomarker and prevention targets relevant to the inflammation-to-cancer transition.
IBD patients have higher risk of colitis-associated colorectal cancer; this study suggests dietary choline might protect the intestinal barrier and reduce inflammation-driven tumor risk via a nutrient–transporter–Notch1...
Distinguishing colorectal cancer from IBD-related inflammatory thickening can be challenging but crucial for treatment decisions. If validated, DECT parameters could offer a noninvasive tool to improve diagnostic...
Preclinical data suggest blocking STAT3 with TTI-101 prevented colitis-associated colorectal tumors in a mouse model and altered tumor-related gene expression and the gut microbiome — findings that could guide future...
This work looks for molecular signals that might help explain how long-term ulcerative colitis can be connected to higher colorectal cancer risk. Identifying shared genes and spatial patterns could eventually guide...
New oral micro- and nanomedicine strategies aim to deliver drugs more selectively to diseased areas in the gut, which could eventually improve treatments for IBD and colorectal cancer by increasing local effects and...
The review suggests LJF contains compounds that may reduce intestinal inflammation, support gut barrier health, and influence microbiota—areas directly relevant to ulcerative colitis and colorectal cancer risk. However,...
The review suggests that specific Klebsiella pneumoniae strains could connect chronic IBD inflammation with rectal cancer risk, pointing to possible biomarker or prevention targets that may be relevant for people with...
Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Ulcerative colitis, Colorectal cancer, and Diet and lifestyle. The original article is from Food science &...
The paper suggests that reduced folate transport can raise markers of inflammation-associated colon tumor initiation in mice, which is relevant because people with IBD are at higher risk for folate deficiency and colon...
The paper identifies a molecular pathway (miR-31-5p/SATB2) linked to UC progression to colitis-associated cancer and reports that resveratrol modulates this axis in mice, suggesting a potential preventive mechanism worth...
Researchers found a candidate shared microbial signal across colorectal cancer, Crohn’s disease, and liver cirrhosis that points to redox-related microbial functions; this could guide future biomarker or experimental...
Family history of CRC raises an individual’s absolute CRC risk whether or not they have IBD, and people with IBD who have multiple first‑degree relatives with CRC appear to have the largest increase in absolute risk....
Dysplasia detection during colonoscopy is central to preventing colorectal cancer in people with IBD. AI tools could help, but current models often fail in inflamed or IBD-specific settings, so this review outlines...
Piezo channels appear central to how mechanical signals influence the gut barrier, immunity, and secretion — processes that can affect inflammation and symptoms in IBD, IBS, and colon cancer. Understanding them could...
People with IBD already have a higher baseline risk of colorectal cancer. This study finds that having multiple first‑degree relatives with CRC adds the largest absolute additional risk, which could affect how...
People with IBD are at higher risk for colorectal cancer; identifying stromal genes that track inflammation-driven EMT could help researchers find biomarkers or targets that explain how chronic inflammation promotes...
This study helps set expectations about short-term risks after right-sided segmental colectomy for Crohn's disease compared with colon cancer. Knowing that overall complication rates were similar but infections were more...
The study identifies distinct fecal bile acid signatures in CRC versus UC that might help develop noninvasive tests to distinguish malignancy from chronic inflammatory disease of the colon.
Researchers are exploring ferroptosis as a double-edged mechanism: preventing it may protect healthy gut lining in IBD, while inducing it might help treat colorectal cancer. Advances could lead to new biomarkers or...
Research linking ETBF to intestinal inflammation and colorectal cancer suggests better detection and targeted therapies for this microbe could eventually affect IBD management and cancer risk assessment.
Fucosylation appears to influence intestinal barrier function, host–microbiota interactions, and immune responses — processes central to IBD pathogenesis. If validated, fucosylation-related biomarkers or therapies could...
Basal crypt dysplasia is easy to miss but linked to higher risk of advanced colorectal neoplasia in longstanding IBD. Improved recognition and use of p53 immunohistochemistry or complementary biomarkers could affect...
Colon-targeted delivery systems aim to concentrate drugs in the colon, which could improve effectiveness and reduce systemic side effects for IBD and colorectal cancer treatments. Understanding these approaches helps...
The study links activation of the cGAS–STING immune-sensing pathway to NF-κB–driven inflammation and tumor formation in UC models, which could help explain mechanisms behind colitis-associated colorectal cancer risk.
This model could improve how researchers study IBD inflammation and early colorectal cancer in a human-derived, multicellular system that reproduces neuromuscular function and immune responses. That may speed preclinical...
LRMDA may be a previously unrecognized protein important for mucus production and intestinal barrier integrity — processes directly relevant to IBD flares, infection risk, and colorectal cancer development. Understanding...
The study introduces a phylogeny-aware AI method that may improve detection and interpretation of microbiome signatures linked to IBD and colorectal cancer, which could help research into microbial biomarkers relevant to...
People with ulcerative colitis face a higher colorectal cancer risk driven in part by chronic inflammation; this review explains the molecular and immune mechanisms behind that risk and highlights biomarkers and...
New high-resolution, multilayer imaging tools can reveal how immune cells, epithelium, and enteric nerves interact in the intestine—processes central to IBD, colorectal cancer risk, and gut-brain disorders.
The study reports a targeted nanoparticle designed to deliver celastrol selectively to inflamed intestinal tissue and colorectal tumors, which could—if translated successfully—address limitations of oral celastrol and...
Better triage methods that combine FIT with demographics and blood biomarkers could reduce unnecessary colonoscopies while keeping sensitivity for colorectal cancer and other serious findings, which matters for...
Smoking-related products may influence Crohn’s disease recurrence after surgery; patients and clinicians may want to be aware of new data comparing heat-not-burn tobacco and e-cigarette use to nonsmoking after ileocolic...
Dysplasia is the key premalignant change that raises colorectal cancer risk in people with colonic IBD. Better detection and clearer management pathways can reduce cancer risk and help patients avoid unnecessary surgery.
Researchers and clinicians are exploring how fucose metabolism affects gut barrier function, immunity, and microbiota — processes central to IBD and colorectal cancer. If validated, fucosylation biomarkers or treatments...
Researchers and clinicians looking for blood- or tissue-based molecular tests for IBD may find these integrated transcriptomic analyses useful because they identify candidate diagnostic biomarkers and highlight shared...
Early, noninvasive biomarkers could help detect ulcerative colitis and related colorectal cancer risk sooner. This study identifies four serum-accessible proteins with promising diagnostic accuracy in the reported...
