Dysplasia

People with IBD have higher risk of several GI and hepatobiliary cancers; imaging is an important complement to endoscopic surveillance for detecting cancers that may be transmural or outside endoscopic reach.

Basal crypt dysplasia is easy to miss but linked to higher risk of advanced colorectal neoplasia in longstanding IBD. Improved recognition and use of p53 immunohistochemistry or complementary biomarkers could affect...

Surveillance colonoscopies in IBD are meant to detect dysplasia or cancer; this report shows some solitary polyps may be benign retention polyps. Correct endoscopic removal and pathology spare patients from unnecessary...

Dysplasia is the key premalignant change that raises colorectal cancer risk in people with colonic IBD. Better detection and clearer management pathways can reduce cancer risk and help patients avoid unnecessary surgery.

If you have PSC-IBD or care for someone who does, this study suggests the gut microbiota and its ability to make secondary bile acids may help drive inflammation and colorectal dysplasia risk.

This study helps distinguish patterns of colorectal dysplasia seen in people without IBD from those seen in IBD, which may affect how pathologists and clinicians interpret biopsy findings and consider cancer risk and...

The study will prospectively evaluate how often dysplasia occurs, how lesions look and behave after endoscopic resection, and what factors predict local or distant recurrence—information that could change surveillance...

People with ulcerative colitis undergo surveillance for dysplasia because of an increased risk of colorectal cancer. This case highlights a pathology pattern (pseudocarcinomatous invasion) that can mimic invasive...

People with long-standing ulcerative colitis face an increased risk of colorectal cancer; this study highlights PPARGC1A as a gene that may be downregulated early in that progression, which could eventually help identify...