Resection, ostomy, J-pouch, strictureplasty, fistula, abscess, and other procedure-related updates.
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Many people with IBD also have inflammatory joint disease. This combined clinic model aimed to provide simultaneous gastroenterology and rheumatology assessment and shared decision-making, and the study reports frequent...
This change may make starting Skyrizi more convenient for adults with Crohn's disease by allowing subcutaneous induction at home using an on‑body injector, rather than requiring clinic IV infusions. It also represents an...
MSC therapy and its interaction with autophagy could point to new ways to boost cell-based treatments for IBD. For people with Crohn's disease or ulcerative colitis, this could eventually lead to different therapeutic...
Based on the title and source metadata, this appears to be a case report related to Procedures and surgery. The original article is from Radiology Case Reports.
People hospitalized with acute severe ulcerative colitis face a high risk of steroid failure and need for rescue therapy or colectomy. This trial explores whether adding the JAK inhibitor tofacitinib to corticosteroids...
Postoperative intra-abdominal abscesses are a common, serious short-term complication after ileocecal surgery in children with Crohn’s disease and can lengthen hospital stay and delay restarting medical treatment.
This analysis suggests delivery method for the same anti‑TNF (infliximab) may affect long‑term clinical and endoscopic outcomes in ileal-predominant Crohn’s disease. If confirmed, route of maintenance dosing could...
Long waits for IBD-related surgery were linked to poorer quality of life in this study, especially when waiting exceeded 1 year. That suggests delays could meaningfully affect daily functioning for people with Crohn’s or...
Hospitalized patients with moderate-to-severe ulcerative colitis flares sometimes need escalation to biologic or surgical treatments. This trial is testing whether a short course of HBOT can improve symptoms and reduce...
This study tests a novel method to deliver healthy mitochondria to the gut lining and reports improved cellular energy, barrier function, and decreased oxidative stress in a mouse model of ulcerative colitis—suggesting a...
This preclinical study describes a new cell‑based approach — macrophages engineered to secrete IL‑10 — that reduced inflammation and improved colon outcomes in a mouse colitis model, suggesting a potential avenue for...
People with Crohn’s disease who have had, or will have, intestinal surgery may benefit from better tools to predict early complications and endoscopic recurrence. Predictive models could help tailor follow-up and...
People with PSC who undergo liver transplant — especially those who have IBD at the time of transplant — remain at elevated risk for colorectal neoplasia, IBD flare or new-onset IBD, and for PSC recurrence. Knowing this...
A patient describes recovering from severe Crohn’s-related malnutrition and living with an ileostomy, then regaining weight and muscle after reversal—topics many people with IBD face. The story highlights practical...
Personal recovery stories can offer hope and practical ideas for people with Crohn’s who are dealing with malnutrition, body-image issues, ostomy surgery, or post-surgical recovery.
New Phase III data on guselkumab are directly relevant because they report long-term (3-year) maintenance results for Crohn’s disease and one-year fistula outcomes for people with perianal disease — areas that affect...
Personal stories like this show how surgery, nutrition, and tailored exercise can help someone with Crohn’s rebuild strength, body weight, and confidence. They can offer practical ideas and emotional encouragement to...
Long-term risk of needing another intestinal surgery is a major concern for people with Crohn’s disease. This study suggests laparoscopic resection may be linked to lower long-term reoperation risk compared with open...
Early intestinal resection is uncommon but important in pediatric Crohn’s disease. Identifying features linked to surgery soon after diagnosis can help families and clinicians monitor higher-risk children and plan care.
Distinguishing inflammation from irreversible fibrosis is a common clinical challenge in Crohn’s disease because it affects treatment choices (medical therapy versus surgery). Validated MRI biomarkers could improve...
People with Crohn’s disease facing pelvic exenteration or urinary diversion may worry that using ileal tissue is unsafe. This study suggests ileal conduits can be done but carry higher urological complication and...
Perianal fistulizing Crohn's disease is a frequent, hard-to-treat complication; molecular and multiomic advances could lead to biomarkers that help choose better-targeted therapies and improve surgical–medical decision...
This trial is testing a novel stem-cell infusion approach aimed at treating Crohn’s disease and ulcerative colitis, so people with IBD may be interested in emerging cell-therapy options and safety data. Phase 1 studies...
This study looks directly at whether failing multiple biologic drugs before elective subtotal colectomy affects short-term surgical outcomes for people with ulcerative colitis — information that can help patients and...
Perianal fistulas are a common, challenging Crohn's complication that often need combined medical and surgical care; understanding local practice patterns helps patients and clinicians anticipate typical treatments and...
The study offers a validated tool to estimate risk of postoperative recurrence after ileocolonic resection and shows that postoperative biologic prophylaxis markedly lowers early endoscopic recurrence—information that...
Firsthand accounts show the real-life impact of ulcerative colitis on daily life, schooling, and mental health. Stories about surgery and ostomy reversal can help reduce stigma and highlight the importance of peer...
The study suggests a colon-targeted herbal treatment altered metabolic and immune pathways and reduced inflammation in a rat model of ulcerative colitis, which could point to new therapeutic approaches to explore for UC...
The study explores whether people with UC in deep histologic remission can reduce or stop maintenance medications without losing remission — a question many patients and clinicians face because of medication costs, side...
Based on the title and source metadata, this appears to be a video related to Procedures and surgery. The original article is from hmpgloballearningnetwork.com.
Based on the title and source metadata, this appears to be a guideline related to Ulcerative colitis, Inflammatory bowel disease, and Colectomy. The original article is from Techniques in Coloproctology.
Surgical site infection is a common and serious complication after IBD surgery. The paper highlights that antibiotic-resistant bacteria (ESBLs, MRSA) were common in this Saudi cohort and that standard cephalosporin...
FMT is shown here to be an effective option for treating recurrent C. difficile infection, including for patients who also have IBD — a group often vulnerable to recurrent infections and complications.
For people hospitalized with acute severe UC, the findings suggest that measuring early infliximab pharmacokinetics could help personalize rescue therapy and potentially reduce colectomy risk by identifying who may need...
Based on the title and source metadata, this appears to be an opinion or commentary related to Ulcerative colitis, Inflammatory bowel disease, and Tests and monitoring. The original article is from Translational...
A registry focused on "difficult-to-treat" IBD aims to describe how often and why patients become treatment-refractory, how their disease and treatments evolve over time, and which outcomes (hospitalization, surgery,...
This early-phase trial explores a novel, targeted bacteriophage treatment for pouchitis linked to an Aeromonas-associated pathogen (MTB). For people with pouchitis after IPAA, a safe, effective phage therapy could...
Patients with IBD have an increased colorectal cancer risk, and those with PSC, extensive colitis, severe inflammation, or prior dysplasia are at especially high risk. High-quality surveillance techniques can improve...
The study provides first human evidence that a single colonoscopic FMT can eradicate mucosal adherent-invasive E. coli (AIEC), a bacterium linked to Crohn’s disease, and it shows associated shifts in mucosal microbiota...
This study explores a non-drug dietary supplement approach aimed at changing host–microbiome interactions after surgery — a potentially relevant prevention strategy for postoperative Crohn's disease recurrence if later...
Telenursing is increasingly used for chronic IBD care; understanding the limits and system factors that affect remote assessment matters because it influences how reliably nurses can detect and respond to flares and...
Decisions about when to build an ileal pouch after emergency colectomy matter to patients because timing could affect recovery, complications, and long-term pouch function. This study suggests timing within or after 6...
TG2 produced by intestinal myofibroblasts may drive fibrosis and strictures in Crohn's disease independently of inflammation; blocking TG2 reduced fibrosis in lab and mouse models, pointing to a possible new...
The study suggests that using infliximab as first-line therapy (rather than IV corticosteroids) may produce more durable remission and reduce long-term colectomy risk in moderate-to-severe ulcerative colitis.
Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Procedures and surgery. The original article is from Gut.
Perianal fistulizing Crohn's disease causes major quality-of-life problems and is often hard to treat. This trial tests risankizumab in people who did not respond to or could not tolerate other standard therapies, and it...
This OLE study follows patients who lost response to ustekinumab every-8-week dosing and evaluates whether increasing to every-4-week dosing maintains efficacy and safety long-term. That question is directly relevant to...
Perianal Crohn’s disease causes major symptoms and affects long-term outcomes; understanding surgical options and the role of combined medical–surgical care can help patients and clinicians plan treatment. The review...
