Resection, ostomy, J-pouch, strictureplasty, fistula, abscess, and other procedure-related updates.
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Subtopics
Surveillance colonoscopies in IBD are meant to detect dysplasia or cancer; this report shows some solitary polyps may be benign retention polyps. Correct endoscopic removal and pathology spare patients from unnecessary...
Distinguishing Crohn’s disease from intestinal tuberculosis can change treatment (immune suppression versus anti‑tubercular therapy) and outcomes. This review summarizes which findings have tended to favor one diagnosis...
People with Crohn's disease who develop symptomatic intestinal strictures currently often need endoscopic dilation or surgery. This trial tests an investigational oral drug (ontunisertib) aiming to improve...
Perianal fistulas are a serious, common complication of Crohn's disease that are often difficult to heal. This study tests a real-world combination of surgery plus an approved IL-23 inhibitor (mirikizumab) to see if...
This paper explores whether individualized integrative management including traditional Chinese medicine might influence outcomes in patients with biologic‑refractory, surgery‑intended acute severe ulcerative colitis — a...
Adding a mesalazine retention enema to oral mesalazine improved short-term symptom relief and endoscopic signs of mucosal healing in mild-to-moderate left-sided ulcerative colitis in this retrospective study. That could...
A formulation that keeps budesonide at the colon surface longer and protects the mucosa could enhance topical treatment for ulcerative colitis and improve mucosal healing compared with standard enemas.
Capsule endoscopy can safely help diagnose small-bowel disease in very young children, including cases of suspected IBD, and may be particularly helpful when blood tests or imaging suggest inflammation or low albumin....
Unexplained mid‑esophageal ulcers with recurrent oral ulcers can reflect rare systemic inflammatory diseases such as gastrointestinal Behçet disease, and they often need broad testing to exclude infections, malignancy,...
Perianal fistulas are a common and morbid complication of Crohn's disease in children; a reliable, less burdensome imaging tool could help assess severity and monitor response to therapy more often than MRI.
The work links a specific post-transcriptional regulator (AUF1) to barrier dysfunction in UC and demonstrates that AUF1-restored organoids can enhance mucosal repair in mice, suggesting a possible new regenerative...
The article reviews current and emerging IBD treatments and the biological reasons they may work — useful for patients wanting to understand treatment options and future directions. It highlights therapies beyond...
People with IBD on biologics or small molecules who live in or travel to areas where Coccidioides is endemic face a measurable risk of coccidioidomycosis. How the infection is classified (proven/probable/possible)...
A dedicated Crohn’s and Colitis Center can coordinate advanced diagnostics, medical and surgical care, nutrition, and mental-health support — all of which can improve symptom management and quality of life. It also...
Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Procedures and surgery. The original article is from gastroendonews.com.
Coexistence of ulcerative colitis and collagenous colitis is rare but can change diagnosis and management. Stool calprotectin and biopsies helped identify and monitor disease activity, and adjusting mesalazine coincided...
Cure8 found this source from journals.lww.com, but the page could not be read reliably yet. It is tagged for Ileocecal Resection and Procedures and surgery. Open the original article for the full details.
Patients with UC who fail both anti-TNF and JAK inhibitor therapies have limited options. This report suggests tacrolimus can be used as a short-term bridge or in combination to reach another maintenance drug, with many...
An uncommon oropharyngeal mass due to Crohn’s disease can be diagnostically challenging and may not respond to corticosteroids or anti-TNF therapy. For some patients, switching to a different mechanism (here, a JAK...
People with IBD (Crohn’s disease or ulcerative colitis) can develop vitamin K deficiency from malabsorption; this label clarifies that Vitamin K1 Injection is indicated for such situations and highlights important safety...
Planned synthesis of global surgical rates and outcomes in the biologics era could help clinicians, patients, and researchers understand how often surgery is needed, what types of operations are performed, and common...
People with IBD and clinicians often face decisions about whether to stop biologics or small molecules before abdominal surgery.
Because it describes a severe new Crohn’s disease case temporally linked to COVID‑19, patients and clinicians should be aware that persistent or worsening GI symptoms after SARS‑CoV‑2 infection may merit investigation;...
Patients with ulcerative colitis and PSC face higher risk of pouch inflammation after IPAA. The study reports fewer pouchitis events among the small group who received antibiotics or immunosuppression, which could...
For people hospitalized with acute severe ulcerative colitis, starting a JAK inhibitor together with IV steroids right away (rather than waiting for steroids to fail) could potentially control inflammation sooner and...
Improving colon-targeted delivery of mesalamine could increase drug concentrations at inflamed tissue and reduce release in the stomach and small intestine, which may improve effectiveness and reduce off-target exposure.
Persistent perineal sinus is a common and impactful complication after proctectomy for Crohn disease that can prolong recovery and require further care. Knowing rates of healing and risk factors can help patients and...
This work explores a novel, programmable way to deliver anti-inflammatory protein therapy (IL-10) directly in the gut using engineered yeast and wearable electronics. If further developed and translated, it could offer a...
Because intestinal lymphoma can closely mimic Crohn’s disease, recognizing red flags (severe malabsorption, proximal small-bowel involvement, monoclonal gammopathy, poor response to IBD therapy) can change diagnosis and...
Cure8 found this source from Gastroenterology report, but the page could not be read reliably yet. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Procedures and surgery. Open the original article...
The video demonstrates a bowel-preserving robotic surgical technique for ileal strictures in Crohn's disease that could help surgeons perform technically demanding intracorporeal suturing and preserve bowel length.
People with PCD often move from pediatric to adult care during late adolescence, and without structured transition programs they can drop out of care. Using an established transition framework could help maintain...
Joint inflammation is a common and impactful extraintestinal issue in IBD; recognizing and treating it appropriately affects symptoms, function, and quality of life.
Intestinal ultrasound is increasingly used to evaluate Crohn’s disease because it’s noninvasive, repeatable, and can detect activity and some complications—potentially reducing reliance on more invasive tests. Wider...
Someone with Crohn’s disease and limited remaining small intestine may face high-risk surgical choices. This case report suggests a specialized oral supplement used with conservative care was associated with fistula...
This study addresses whether being on biologic or small‑molecule IBD drugs before colorectal surgery affects short‑term postoperative complications — a practical concern for patients and clinicians planning surgery.
The T&W criteria are still used to define severe UC on admission, but relying on them alone may delay recognition of steroid non‑response and escalation decisions. Integrating biomarkers, endoscopy, and imaging can help...
Better delineation of colitis‑associated neoplasia can improve the chance of complete endoscopic removal and help find residual disease that white‑light imaging may miss.
This preclinical study links periodontal ligament stem cells to reduced colitis severity in mice by restoring macrophage mitochondrial function and activating PINK1/Parkin-associated mitophagy, suggesting a possible new...
Intestinal endometriosis can mimic Crohn’s disease and, in rare cases, lead to life‑threatening bowel necrosis requiring emergency surgery. Awareness may prompt consideration of alternate diagnoses in atypical or...
Short-term mental health problems (depression, anxiety, adjustment disorders) appear more common after ostomy creation than after nonostomy IBD surgery among biologic-treated adults. Awareness may help patients and...
A colon-targeted 5-ASA pellet could improve delivery of mesalamine to the diseased colon while reducing release in the stomach; that might increase effectiveness or reduce systemic exposure compared with standard...
This study presents a targeted immunotherapy approach designed to concentrate an immune‑modulating protein (PD‑L1‑Fc) in the inflamed colon, which could in future reduce systemic side effects of biologic immunomodulators...
Patients and clinicians are interested in whether combining two targeted biologic therapies can induce stronger endoscopic healing for people with difficult-to-treat Crohn's disease, and whether benefit can be maintained...
People with an ileal pouch after UC/IBDU often struggle with fecal incontinence and reduced quality of life. This trial is testing a noninvasive device (Emsella chair) aimed at improving incontinence and patient-reported...
Surgical care for Crohn’s disease affects many patients with complicated disease. The study suggests modern practice increasingly uses laparoscopic approaches and sees fewer emergency surgeries and stomas, which can mean...
Pouch-related fistula is a serious late complication after IPAA. The study suggests people with UC who undergo IPAA may have higher fistula risk than patients with FAP, and that inflammatory pouch disease (like...
Cure8 could only read part of this source from PubMed Central, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Infliximab, and Azathioprine.
