Medication topics

Corticosteroids

Corticosteroid articles covering steroid treatment, side effects, tapering, safety, and IBD flare management. Medication context emphasizes treatment decisions, safety, approvals, and therapy access.

30 articles

Aminosalicylate use Increases Corticosteroid Exposure and Decreases Biologic Durability in Pediatric Crohn's Disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Aminosalicylate use Increases Corticosteroid Exposure and Decreases Biologic Durability in Pediatric Crohn's Disease.

This study suggests that using 5‑ASA drugs early in children with Crohn’s disease was common but linked to more steroid use, delayed biologic treatment, and lower biologic durability — outcomes that matter for long‑term...

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Living with Primary Immunodeficiencies: CVID—Enteropathy from the Perspective of a Gastroenterologist
Journal of Human Immunity

Living with Primary Immunodeficiencies: CVID—Enteropathy from the Perspective of a Gastroenterologist

CVID-related enteropathy can resemble celiac disease or IBD, carries high morbidity and mortality, and often does not respond to standard immunoglobulin therapy — patients and clinicians need awareness of its distinct...

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Clinical and endoscopic features of checkpoint inhibitor-induced colitis and their association with selective immunosuppressive therapy use.
Inflammatory bowel diseases

Clinical and endoscopic features of checkpoint inhibitor-induced colitis and their association with selective immunosuppressive therapy use.

People receiving immune checkpoint inhibitors who develop colitis may face different risks of needing stronger immunosuppression depending on the ICI drug class. Understanding which features predict escalation could...

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Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review).
International journal of molecular medicine

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review).

The article reviews current and emerging IBD treatments and the biological reasons they may work — useful for patients wanting to understand treatment options and future directions. It highlights therapies beyond...

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Characterization of remission levels in patients with ulcerative colitis treated with 5-aminosalicylates: results of the cross-sectional CARUC-ASA study by the Belgian IBD Research and Development Group.
Journal of Crohn's & colitis

Characterization of remission levels in patients with ulcerative colitis treated with 5-aminosalicylates: results of the cross-sectional CARUC-ASA study by the Belgian IBD Research and Development Group.

The study evaluates how well first-line 5-ASA therapy achieves modern treatment targets (endoscopic, histologic, and biomarker remission) in real-world UC patients who are clinically in remission. Patients and clinicians...

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Management of Ulcerative Colitis after Mesalamine-Induced Myocarditis: Successful Treatment with Upadacitinib - A Case Report.
Inflammatory intestinal diseases

Management of Ulcerative Colitis after Mesalamine-Induced Myocarditis: Successful Treatment with Upadacitinib - A Case Report.

Mesalamine can rarely cause myocarditis, creating a challenge for ongoing UC treatment. This report shows upadacitinib was used successfully as an alternative when biologics were considered higher cardiac risk and...

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A survey on the practices and patterns in the management of acute severe ulcerative colitis in India
Intestinal Research

A survey on the practices and patterns in the management of acute severe ulcerative colitis in India

A nationwide clinician survey identifies major variation in how acute severe ulcerative colitis is diagnosed, monitored, and when rescue therapy or surgery is used — differences that can affect patient outcomes and...

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Effectiveness of tofacitinib as rescue therapy in biological-naive patients with steroid-refractory acute severe ulcerative colitis: a multicentric retrospective analysis.
European journal of gastroenterology & hepatology

Effectiveness of tofacitinib as rescue therapy in biological-naive patients with steroid-refractory acute severe ulcerative colitis: a multicentric retrospective analysis.

This study suggests tofacitinib may work quickly as a rescue option for biologic‑naive patients with steroid‑refractory ASUC and that many achieved steroid‑free remission by 24 weeks — information that could matter when...

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Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.
Journal of clinical medicine

Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.

This study describes how IBD presents and early outcomes in children at a tertiary center, noting high rates of inflammation, nutritional problems, and early flares. Findings may help families and clinicians understand...

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Isolated Transverse Colon Perforation During Corticosteroid Tapering in Quiescent Systemic Lupus Erythematosus: A Histopathology-Supported Diagnosis of Exclusion
Cureus

Isolated Transverse Colon Perforation During Corticosteroid Tapering in Quiescent Systemic Lupus Erythematosus: A Histopathology-Supported Diagnosis of Exclusion

GI perforation is a serious, potentially life-threatening complication that can occur in people with autoimmune diseases; this report highlights that perforation can happen during corticosteroid tapering and that careful...

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