Diarrhea, abdominal pain, fatigue, bleeding, urgency, flares, remission, and symptom management news.
Page 1 of 9 · 398 articles
Subtopics
Accurate diagnosis and classification affect treatment choices and risks—misdiagnosis can lead to unnecessary immunosuppression, while misclassification can under-recognize severe or proximal disease that needs different...
Validated patient-reported measures help track how IBD affects daily function and well-being. A Turkish IBD-Disk gives clinicians and researchers a standardized way to measure patient-perceived disease burden and monitor...
AHR signaling may influence epithelial inflammation in IBD and could be a potential target for future therapies or biomarker research. Findings are preliminary but point to IL‑8 as a responsive inflammatory mediator in...
Definitions of "disease burden" vary a lot, which makes it hard to compare studies or to ensure care and research address what matters most to people with Crohn's. A unified, multidimensional framework could help...
The study links common eating habits (fast food, fizzy drinks, spicy foods) with Crohn’s in this sample, which may help patients and clinicians think about dietary patterns worth discussing. It’s relevant because diet is...
Depression and IBD often co-occur; knowing that each can precede the other helps patients and clinicians monitor mental health and GI symptoms more proactively.
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Irritable bowel syndrome, and Symptoms and flares. The original article is from msn.com.
Malnutrition is common in IBD and linked to worse quality of life and outcomes. Validating a standardized GLIM approach could help clinicians identify and treat malnutrition earlier and more consistently in people with...
This study links brain structure and function differences to clinical measures and neurotransmitter systems in Crohn’s disease, which may help explain cognitive, mood, or quality-of-life effects some people with CD...
This review connects enteric sensory neuron dysfunction to symptoms common in IBS and IBD (pain, diarrhea, constipation, dysmotility). Understanding IPAN plasticity could point to new treatment targets that act locally...
The study suggests Crohn’s disease is associated with coordinated brain structure and function differences that relate to disease activity and quality of life, pointing to brain–gut links that could inform future...
Findings suggest a dietary flavonoid (daidzein) may reduce colitis in mice via microbial activation and host signaling pathways, pointing toward microbiome-informed nutritional approaches for IBD.
This study identifies KCTD10 as a regulator of intestinal stem cell function and mucosal repair in experimental colitis, which could point to new mechanistic insights about why epithelial healing fails in some cases of...
If validated, differences in tissue QDPR could become a marker to help differentiate UC from CD and to indicate mucosal antioxidant/repair status, which may be relevant for disease monitoring and research into new...
The study identifies a new monocyte-surface RNA (Y RNAs) that appears higher in an exploratory IBD cohort and amplifies inflammatory signalling in cells and mice, which could point to new biomarker or therapeutic...
An unusual craving to smell non-food substances (desiderosmia) can be a clue to severe iron deficiency anaemia and may point to undiagnosed inflammatory bowel disease in adolescents. Recognising this sign could speed...
This preclinical study suggests clarithromycin may reduce colon inflammation in ulcerative colitis models and identifies Kv1.3 and the Th17/Treg balance as possible mechanisms — findings that could guide future...
Updated treat-to-target recommendations affect how inflammation and symptoms are monitored and when treatments should be changed. Clear targets and timing help patients and clinicians make consistent, evidence-informed...
This study highlights a potential microbiome–bile acid–immune pathway that could be relevant to ulcerative colitis and suggests a traditional herbal formula may influence that pathway in mice. Patients interested in...
A blood biomarker that predicts anti-TNF response could help people with IBD and their clinicians choose the right biologic sooner, avoiding ineffective treatment. This study reports that lower baseline serum oncostatin...
The study links lower vitamin D and higher TNF‑alpha with greater UC severity and with each other, suggesting these measurable biomarkers may reflect inflammation in ulcerative colitis.
Mid-stage data suggest a dual-targeting approach may improve endoscopic remission for people with moderate–severe Crohn's disease, including many who previously failed advanced therapies. If confirmed in larger trials,...
If validated, antibody-based signatures could enable much earlier detection of IBD and help identify people at risk of more severe Crohn’s disease years before symptoms—potentially opening opportunities for research on...
If validated, blood antibody patterns could allow earlier identification of people at risk for Crohn’s disease or ulcerative colitis — potentially before bowel damage occurs — opening opportunities for earlier monitoring...
The study suggests people with IBD consumed more dietary emulsifiers than healthy controls and found initial links between higher UPF/emulsifier intake and worse IBD-related events, which could be important if diet...
Fatigue is a common, disabling issue in Crohn’s disease with unclear biology. This study suggests measurable brain-structure differences correlate with fatigue severity and may modify how disease activity influences...
The study directly compares fatigue levels across several chronic conditions using the same validated tools, offering context for how fatigue in IBD compares to other illnesses. That context can help patients and...
Purinergic signaling connects nerves, immune cells, epithelium, and microbiota in the gut — pathways that can influence inflammation, motility, and pain relevant to IBD. Understanding these mechanisms could point to new...
The study links an experimental treatment (dexpanthenol) to reduced inflammatory cytokines and improved anxiety-like behaviors in a rat colitis model, which is relevant to research on inflammation-driven gut–brain...
Fatigue affects a large share of people with IBD and often persists despite remission; understanding treatment options and the need for a broad care plan can help patients and clinicians set realistic goals and...
Deep remission is an emerging treatment target in Crohn’s disease that combines symptoms and objective measures. A meaningful proportion of patients in VIVID-1 achieved corticosteroid-free deep remission with mirikizumab...
The study suggests a dietary protein (ovotransferrin) can reduce colitis severity in mice by changing the gut microbiota and increasing certain secondary bile acids that lower inflammation and gut permeability.
Capsaicin is commonly consumed and acts on TRPV1, which is increased in inflamed IBD tissue; depending on dose and disease activity it may help or worsen inflammation and symptom-related pain.
Findings suggest GM-CSF signaling may help limit epithelial injury and shape immune cell states in Crohn’s disease, which could be relevant to understanding inflammation and future therapies targeting innate immunity or...
Protein biomarkers that predict IBD years before diagnosis could enable earlier detection, inform risk-stratified monitoring, and reveal early disease pathways that might be targeted to prevent or delay onset.
The paper suggests a specific molecule, MXRA7, links macrophage M1 polarization and epithelial pyroptosis—two processes implicated in ulcerative colitis tissue damage. If validated, this could point to new targets for...
Diarrhea is a common, burdensome symptom in IBD. This study suggests that inflammation-linked defects in enterocyte differentiation and reduced ion transporter expression may help explain persistent diarrhea and that...
Patients and clinicians considering long-term use of mirikizumab for Crohn's disease may find evidence here that quality of life and common symptoms (fatigue, abdominal pain, stool frequency) can remain improved out to...
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from msn.com.
Many people with Crohn’s experience inflammation outside the gut that can affect joints, eyes, skin, gallbladder, kidneys, and bones. Recognizing these signs can help patients and clinicians connect seemingly unrelated...
This study follows people from diagnosis and shows that about half achieve clinically meaningful improvements in quality of life by 3 years, but many remain below general population norms.
The study suggests psychological (emotional) stress can worsen colitis-like inflammation via GSK3β-mediated neuroimmune changes, and that a probiotic (VSL#3) reduced many adverse effects in mice — relevant to...
Based on the title and source metadata, this appears to be a patient education related to Ulcerative colitis, Inflammatory bowel disease, and Symptoms and flares. The original article is from California medicine.
Based on the title and source metadata, this appears to be a patient education related to Ulcerative colitis and Symptoms and flares. The original article is from British medical journal (Clinical research ed.).
The study suggests L‑proline can reduce colitis in a mouse model and reshapes the gut microbiome, raising the possibility that amino-acid–based dietary strategies might influence intestinal inflammation through...
If true, the finding explains why symptoms can return after remission: the gut lining may remain biologically vulnerable even when inflammation seems controlled. That could point to new approaches aimed at 'molecular...
Based on the title and source metadata, this appears to be a patient education related to Ulcerative colitis, Crohn's disease, and Inflammatory bowel disease. The original article is from msn.com.
Based on the title and source metadata, this appears to be a video related to Crohn's disease, Inflammatory bowel disease, and Stricture. The original article is from hmpgloballearningnetwork.com.
