Symptoms and disease activity
Depression articles covering mental health, quality of life, coping, support, and daily functioning for people affected by IBD. Symptom context emphasizes flares, remission, daily disease activity, and patient-relevant warning signs.
20 articles
Depression and IBD often co-occur; knowing that each can precede the other helps patients and clinicians monitor mental health and GI symptoms more proactively.
Depression is more common in people with Crohn’s and can worsen disease outcomes and quality of life. Recognizing and treating depression alongside Crohn’s may improve symptom control, reduce hospitalizations, and lower...
Emotional functioning and parent-child mental health are linked with anxiety, depression, and quality of life in children with IBD and other GI autoimmune disorders. Identifying these issues may help families get...
Fatigue markedly affects quality of life for people with Crohn’s and often remains after inflammation is controlled. Recognizing multiple drivers — psychological distress and immune/hematologic signals — could change how...
Fatigue is extremely common in IBD and is closely linked to depression—recognizing and addressing mental-health issues may be important for patients who report significant fatigue.
If disease activity hurts quality of life partly through low self-efficacy and (for UC) psychological distress, then boosting self-management confidence and identifying anxiety/depression could help improve...
Depression and GI diseases often co-occur; knowing which tends to appear first — and that this varies by subtype — can help clinicians prioritize screening and integrated care.
Many people with IBD remain symptomatic even when tests show little or no inflammation; recognising these persistent symptoms as a separate treatment target could improve quality of life. This reframes care to address...
Fatigue is very common in people with IBD—even when the disease is in remission—and is linked with lower physical activity, more sitting time, and with anxiety/depression. Understanding these links may help patients and...
The study links worse UC activity with higher rates of anxiety and depression and with poorer quality of life among patients in Pakistan, suggesting mental-health screening could be relevant to overall disease...
The review shows psychotherapies can improve quality of life and reduce anxiety and depression in people with IBD, outcomes that matter for daily functioning even when intestinal symptoms may not change.
This study suggests brain glymphatic function — a fluid-clearance system — may be altered in people with Crohn’s disease and could relate to inflammation and common neuropsychiatric symptoms like fatigue, anxiety,...
Mental health problems often begin before IBD is diagnosed and stay higher for years after; addressing psychiatric symptoms early could improve overall disease management and quality of life for people with Crohn’s...
This study suggests erythritol — a common non-nutritive sweetener — may worsen experimental colitis and depression-like behavior in mice via microbiome and metabolic changes, raising questions about how ultra-processed...
Chronic pain affects many people with IBD even after inflammation is controlled, often limiting daily activities and worsening mental health. Understanding that pain can persist without active inflammation highlights the...
Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues...
Fatigue affects many people with Crohn’s even when inflammation looks controlled; recognizing it as a distinct target could change clinic assessments and treatment priorities.
This study suggests risankizumab may improve quality of life and reduce common symptoms (fatigue, mood, urgency) more than ustekinumab for patients with moderate-to-severe Crohn’s disease who didn’t respond to anti-TNF...
Fatigue is a common, often persistent symptom in Crohn’s disease even during remission. This study suggests brain structure differences may be linked to fatigue when inflammation is low, pointing to potential...
The study suggests anxiety, depression, poor sleep, and low exercise are linked with higher risk of IBD flares. That means mental health and lifestyle may be important parts of managing IBD alongside medical care.
