Symptoms and disease activity

Depression

Depression articles covering mental health, quality of life, coping, support, and daily functioning for people affected by IBD. Symptom context emphasizes flares, remission, daily disease activity, and patient-relevant warning signs.

11 articles

Association between Ulcerative Colitis, mental health, and Quality of Life in a Pakistani cohort: A cross-sectional analysis
PLOS One

Association between Ulcerative Colitis, mental health, and Quality of Life in a Pakistani cohort: A cross-sectional analysis

The study links worse UC activity with higher rates of anxiety and depression and with poorer quality of life among patients in Pakistan, suggesting mental-health screening could be relevant to overall disease...

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Efficacy of psychotherapies in individuals with inflammatory bowel disease: A systematic review and meta-analysis
World Journal of Psychiatry

Efficacy of psychotherapies in individuals with inflammatory bowel disease: A systematic review and meta-analysis

The review shows psychotherapies can improve quality of life and reduce anxiety and depression in people with IBD, outcomes that matter for daily functioning even when intestinal symptoms may not change.

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Multimodal MRI reveals glymphatic system activity associated with systemic inflammation and neuropsychiatric symptoms in Crohn’s disease
Journal of Gastroenterology

Multimodal MRI reveals glymphatic system activity associated with systemic inflammation and neuropsychiatric symptoms in Crohn’s disease

This study suggests brain glymphatic function — a fluid-clearance system — may be altered in people with Crohn’s disease and could relate to inflammation and common neuropsychiatric symptoms like fatigue, anxiety,...

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Erythritol Exacerbates DSS-Induced Colitis and Influences Behavioral Responses in Mice Through Gut Microbiota and Metabolic Alterations
Microorganisms

Erythritol Exacerbates DSS-Induced Colitis and Influences Behavioral Responses in Mice Through Gut Microbiota and Metabolic Alterations

This study suggests erythritol — a common non-nutritive sweetener — may worsen experimental colitis and depression-like behavior in mice via microbiome and metabolic changes, raising questions about how ultra-processed...

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Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.
Journal of psychosomatic research

Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.

Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues...

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