Cure8
Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.
Journal of psychosomatic research

Cure8 research brief

Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.

1 min read
Mental health and quality of life Anxiety Depression Clinical study Adult patients Clinicians Researchers Parents Caregivers

Why This Matters

Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues could help address sexual health problems in people with IBD.

Who Should Pay Attention

Adults with IBD, gastroenterology clinicians and IBD care teams, mental-health providers, and researchers focused on IBD quality-of-life.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

This cross-sectional study of 219 people with IBD (105 Crohn’s, 114 UC) measured sexual dysfunction (ASEX), muscle-related functional reserve (handgrip, muscle mass, gait speed), and psychological symptoms (HADS).

Sexual dysfunction was common (60.7%) and showed correlations with older age, female sex, higher depressive and anxiety symptoms, greater disease activity (Harvey-Bradshaw Index), and lower gait speed/muscle measures.

In hierarchical regression, depressive symptoms added significant explanatory power and in the final model older age, female sex, and depressive symptom burden were independently associated with worse ASEX scores.

This paper’s main take-home is that psychological and demographic factors explained more of the variation in sexual dysfunction than disease activity or sarcopenia-related measures, supporting routine psychosocial assessment in IBD care.

Keep In Mind

Cross-sectional design limits causal inference. Findings are based on measures reported in the article abstract and should be interpreted as study-level associations rather than proof of effect.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationJournal of psychosomatic research
AuthorsMelez SNI, Barutcu S, Cansel N +1 more
Study typeIm, journal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedJul 14, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

Related Reading

Browse latest news →