Mental health and quality-of-life topics

Fatigue

Fatigue articles covering tiredness, anemia, inflammation, mental health, quality of life, and daily functioning in IBD. Quality-of-life context emphasizes daily functioning, mental health, fatigue, and support.

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Beyond the pelvis: redefining endometriosis as a systemic inflammatory disorder. A systematic review and meta-analysis.
Autoimmunity reviews

Beyond the pelvis: redefining endometriosis as a systemic inflammatory disorder. A systematic review and meta-analysis.

If endometriosis is linked to other immune, allergic, or chronic pain conditions, people with endometriosis may benefit from broader evaluation and coordinated care beyond gynecology. The review suggests shared...

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Updated treatment targets in inflammatory bowel disease (STRIDE-III): an initiative of the International Organization for the Study of IBD.
The lancet. Gastroenterology & hepatology

Updated treatment targets in inflammatory bowel disease (STRIDE-III): an initiative of the International Organization for the Study of IBD.

Updated treat-to-target recommendations affect how inflammation and symptoms are monitored and when treatments should be changed. Clear targets and timing help patients and clinicians make consistent, evidence-informed...

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Fatigue across physical and mental health conditions: results from a multicenter study at the German Center for Mental Health.
Journal of psychosomatic research

Fatigue across physical and mental health conditions: results from a multicenter study at the German Center for Mental Health.

The study directly compares fatigue levels across several chronic conditions using the same validated tools, offering context for how fatigue in IBD compares to other illnesses. That context can help patients and...

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Digital cognitive behavioural self-management programme for fatigue, pain, urgency and incontinence in inflammatory bowel disease
Translational gastroenterology and hepatology

Digital cognitive behavioural self-management programme for fatigue, pain, urgency and incontinence in inflammatory bowel disease

Based on the title and source metadata, this appears to be an opinion or commentary related to Inflammatory bowel disease, Fatigue, and Pain. The original article is from Translational gastroenterology and hepatology.

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Long-term Benefits of Mirikizumab on Patient-Reported Outcomes in Individuals with Crohn's Disease: 2-Year Results from the VIVID-2 Extension Study.
Clinical and translational gastroenterology

Long-term Benefits of Mirikizumab on Patient-Reported Outcomes in Individuals with Crohn's Disease: 2-Year Results from the VIVID-2 Extension Study.

Patients and clinicians considering long-term use of mirikizumab for Crohn's disease may find evidence here that quality of life and common symptoms (fatigue, abdominal pain, stool frequency) can remain improved out to...

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Health-related quality of life after diagnosis of ulcerative colitis and Crohn’s disease: 3-year trajectories and factors associated with clinically meaningful improvement (the IBSEN III cohort)
Inflammatory Bowel Diseases

Health-related quality of life after diagnosis of ulcerative colitis and Crohn’s disease: 3-year trajectories and factors associated with clinically meaningful improvement (the IBSEN III cohort)

This study follows people from diagnosis and shows that about half achieve clinically meaningful improvements in quality of life by 3 years, but many remain below general population norms.

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Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Mymensingh medical journal : MMJ

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.

Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...

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Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.
Minerva gastroenterology

Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.

Work-related productivity loss was common in this study and linked to both clinical (disease activity, strictures, fatigue) and psychosocial factors (anxiety, depression, self-efficacy, social support).

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Evaluation of a Mental Health Care App-Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial.
JMIR research protocols

Evaluation of a Mental Health Care App-Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial.

Fatigue greatly affects quality of life for people with IBD even in remission; if effective and scalable, a mobile CBT program could offer accessible symptom support. The trial will also examine engagement factors...

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Beyond inflammation control: Rethinking fatigue as a multidimensional target in Crohn’s disease management
World Journal of Gastroenterology

Beyond inflammation control: Rethinking fatigue as a multidimensional target in Crohn’s disease management

Fatigue markedly affects quality of life for people with Crohn’s and often remains after inflammation is controlled. Recognizing multiple drivers — psychological distress and immune/hematologic signals — could change how...

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High Prevalence of Fatigue is Linked to Depression in Inflammatory Bowel Disease.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

High Prevalence of Fatigue is Linked to Depression in Inflammatory Bowel Disease.

Fatigue is extremely common in IBD and is closely linked to depression—recognizing and addressing mental-health issues may be important for patients who report significant fatigue.

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Machine-learning approach to dissect the clinical heterogeneity of IBD-associated fatigue.
BMJ digital health & AI

Machine-learning approach to dissect the clinical heterogeneity of IBD-associated fatigue.

Fatigue affects more than half of people with IBD and is a leading cause of impaired quality of life. A machine-learning approach that identifies distinct patient-level patterns may help researchers and clinicians...

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Low-Dose Naltrexone in Crohn's Disease: A Prematurely Terminated Randomized Trial Showing Reduced Fatigue Without Clinical or Endoscopic Benefit.
Digestive diseases and sciences

Low-Dose Naltrexone in Crohn's Disease: A Prematurely Terminated Randomized Trial Showing Reduced Fatigue Without Clinical or Endoscopic Benefit.

A controlled trial found low-dose naltrexone did not induce endoscopic or clinical remission in Crohn's disease, but it showed a possible benefit for reducing fatigue. Patients seeking symptom relief without...

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High prevalence of fatigue in patients with inflammatory bowel disease: association with physical activity intensity and sedentary behavior
Frontiers in Public Health

High prevalence of fatigue in patients with inflammatory bowel disease: association with physical activity intensity and sedentary behavior

Fatigue is very common in people with IBD—even when the disease is in remission—and is linked with lower physical activity, more sitting time, and with anxiety/depression. Understanding these links may help patients and...

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A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy
ClinicalTrials.gov

A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy

The trial could show whether a smart-label app plus clinician alerts improves medication adherence and downstream clinical outcomes for people with Crohn's disease or ulcerative colitis starting oral or subcutaneous...

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Multimodal MRI reveals glymphatic system activity associated with systemic inflammation and neuropsychiatric symptoms in Crohn’s disease
Journal of Gastroenterology

Multimodal MRI reveals glymphatic system activity associated with systemic inflammation and neuropsychiatric symptoms in Crohn’s disease

This study suggests brain glymphatic function — a fluid-clearance system — may be altered in people with Crohn’s disease and could relate to inflammation and common neuropsychiatric symptoms like fatigue, anxiety,...

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Fatigue in inflammatory bowel disease beyond intestinal inflammation: A cross-sectional study.
Journal of psychosomatic research

Fatigue in inflammatory bowel disease beyond intestinal inflammation: A cross-sectional study.

Fatigue is common and disabling for people with IBD; this study shows that factors beyond intestinal inflammation—especially central sensitization and psychological symptoms—explain much of fatigue. That means treating...

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Acceptability and Feasibility of Mindfulness-Based Cognitive Therapy in Adults with Inflammatory Bowel Disease: A Mixed-Methods Study
Mindfulness

Acceptability and Feasibility of Mindfulness-Based Cognitive Therapy in Adults with Inflammatory Bowel Disease: A Mixed-Methods Study

IBD patients often face high psychological burden; knowing whether MBCT is acceptable and feasible helps patients and clinicians weigh it as a support option. Practical barriers (time, fatigue, disease activity) and...

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Multifaceted burden of short bowel syndrome for patients and caregivers: The landmark survey.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

Multifaceted burden of short bowel syndrome for patients and caregivers: The landmark survey.

Patients with short bowel syndrome and their caregivers can face heavy, multidimensional burdens including dependence on parenteral nutrition/IV hydration, frequent symptoms like fatigue, increased healthcare use, and...

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The Roles of Complementary Structured Exercise and Physical Therapy in The Aging and Older Adult IBD Patient Care Team.
Current treatment options in gastroenterology

The Roles of Complementary Structured Exercise and Physical Therapy in The Aging and Older Adult IBD Patient Care Team.

Older adults with IBD are at higher risk of functional decline; SE and PT are low-risk interventions that may help reduce frailty, sarcopenia, fatigue, joint pain, and improve postoperative recovery and quality of life.

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Psychosocial Experience, Impacts and Management of Fatigue in Young People With Inflammatory Bowel Disease—A Systematic Review
JCC Plus

Psychosocial Experience, Impacts and Management of Fatigue in Young People With Inflammatory Bowel Disease—A Systematic Review

Fatigue is a common, impactful symptom in pediatric and young-adult IBD but is poorly defined and measured, limiting the ability to design age-appropriate supports. This review highlights gaps that affect patients' daily...

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Data-driven subphenotyping uncovers ulcerative colitis subtype with high risk for relapse in Japan: a prospective multicenter cohort study
The Lancet Regional Health - Western Pacific

Data-driven subphenotyping uncovers ulcerative colitis subtype with high risk for relapse in Japan: a prospective multicenter cohort study

The study suggests quality-of-life and patient-reported measures can reveal a subgroup of UC patients in clinical remission who nevertheless have higher relapse risk, which could help personalize monitoring and care.

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Patient Preferences for Inflammatory Bowel Disease Treatment: Results from a Global Survey Conducted in Partnership with the European Federation of Crohn’s & Ulcerative Colitis Associations
The Patient - Patient-Centered Outcomes Research

Patient Preferences for Inflammatory Bowel Disease Treatment: Results from a Global Survey Conducted in Partnership with the European Federation of Crohn’s & Ulcerative Colitis Associations

This global survey shows that people with IBD prioritize symptom relief and psychological well-being over treatment features like administration route or speed of onset. That matters for shared decision-making, trial...

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Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.
Revista da Associacao Medica Brasileira (1992)

Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.

Fear of movement was more common and more severe in people with ulcerative colitis in this study. Addressing kinesiophobia could help increase physical activity and improve function and quality of life for people with...

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Effects of exercise therapy on quality of life in patients with inflammatory bowel disease: a network meta-analysis
Frontiers in Physiology

Effects of exercise therapy on quality of life in patients with inflammatory bowel disease: a network meta-analysis

Exercise is a low-cost, accessible intervention that may improve quality of life and reduce symptoms in people with IBD. This pooled analysis suggests some exercise types — especially regular continuous aerobic exercise...

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Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial
Digestive Diseases and Sciences

Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial

Self‑management programs delivered by nurses may help people with IBD improve daily functioning, confidence in managing their condition, and quality of life even when inflammation markers don’t change. That matters...

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