Mental health and quality-of-life topics

Anxiety

Anxiety articles covering mental health, quality of life, stress, coping, and support for people affected by IBD. Quality-of-life context emphasizes daily functioning, mental health, fatigue, and support.

38 articles

Understanding the Impact of Perceived Stigma on Healthcare Perception and Medication Utilization Among Black Individuals with Inflammatory Bowel Diseases
Digestive Diseases and Sciences

Understanding the Impact of Perceived Stigma on Healthcare Perception and Medication Utilization Among Black Individuals with Inflammatory Bowel Diseases

Perceived stigma may affect how Black people with IBD view their care and whether they stick with medications, which can influence disease management and outcomes. Understanding these links can point to targets for...

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Probiotic-based sequential delivery system for gut-brain co-therapy against inflammatory bowel disease-associated anxiety/depression
Journal of Nanobiotechnology

Probiotic-based sequential delivery system for gut-brain co-therapy against inflammatory bowel disease-associated anxiety/depression

The study presents a novel probiotic-based delivery system that targets both intestinal inflammation and anxiety/depression through the gut–brain axis, a potentially relevant concept for people with IBD who commonly...

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Association between Ulcerative Colitis, mental health, and Quality of Life in a Pakistani cohort: A cross-sectional analysis
PLOS One

Association between Ulcerative Colitis, mental health, and Quality of Life in a Pakistani cohort: A cross-sectional analysis

The study links worse UC activity with higher rates of anxiety and depression and with poorer quality of life among patients in Pakistan, suggesting mental-health screening could be relevant to overall disease...

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A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy
ClinicalTrials.gov

A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy

The trial could show whether a smart-label app plus clinician alerts improves medication adherence and downstream clinical outcomes for people with Crohn's disease or ulcerative colitis starting oral or subcutaneous...

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Efficacy of psychotherapies in individuals with inflammatory bowel disease: A systematic review and meta-analysis
World Journal of Psychiatry

Efficacy of psychotherapies in individuals with inflammatory bowel disease: A systematic review and meta-analysis

The review shows psychotherapies can improve quality of life and reduce anxiety and depression in people with IBD, outcomes that matter for daily functioning even when intestinal symptoms may not change.

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Fatigue in inflammatory bowel disease beyond intestinal inflammation: A cross-sectional study.
Journal of psychosomatic research

Fatigue in inflammatory bowel disease beyond intestinal inflammation: A cross-sectional study.

Fatigue is common and disabling for people with IBD; this study shows that factors beyond intestinal inflammation—especially central sensitization and psychological symptoms—explain much of fatigue. That means treating...

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Short-term psychiatric outcomes after ostomy vs nonostomy surgery in biologic-treated IBD patients.
Inflammatory bowel diseases

Short-term psychiatric outcomes after ostomy vs nonostomy surgery in biologic-treated IBD patients.

Short-term mental health problems (depression, anxiety, adjustment disorders) appear more common after ostomy creation than after nonostomy IBD surgery among biologic-treated adults. Awareness may help patients and...

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Exploring endoscopy sedation experiences in young adults with pediatric-onset inflammatory bowel disease after transfer to adult gastroenterology care.
Journal of the Canadian Association of Gastroenterology

Exploring endoscopy sedation experiences in young adults with pediatric-onset inflammatory bowel disease after transfer to adult gastroenterology care.

Endoscopy comfort and sedation differ between pediatric and adult settings, and worse adult experiences could deter young adults from needed surveillance or care. Addressing sedation choice, communication, and provider...

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Beyond mood: the neurobiological rationale for using SSRIs and SNRIs in the care of inflammatory bowel disease and disorders of gut-brain interaction.
Minerva gastroenterology

Beyond mood: the neurobiological rationale for using SSRIs and SNRIs in the care of inflammatory bowel disease and disorders of gut-brain interaction.

This review suggests SSRIs and SNRIs may influence both brain and gut pathways relevant to symptom burden in IBD and DGBI — potentially improving mood, pain, motility, and aspects of inflammation. That could matter for...

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Ziwu-Liuzhu-guided combined external therapy promotes wound healing in postoperative perianal fistulizing Crohn’s disease
World Journal of Gastrointestinal Surgery

Ziwu-Liuzhu-guided combined external therapy promotes wound healing in postoperative perianal fistulizing Crohn’s disease

Perianal fistulizing Crohn’s disease causes delayed healing and high recurrence after surgery. This study suggests a specific time-guided external traditional therapy may speed wound healing, reduce inflammation, and...

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Data-driven subphenotyping uncovers ulcerative colitis subtype with high risk for relapse in Japan: a prospective multicenter cohort study
The Lancet Regional Health - Western Pacific

Data-driven subphenotyping uncovers ulcerative colitis subtype with high risk for relapse in Japan: a prospective multicenter cohort study

The study suggests quality-of-life and patient-reported measures can reveal a subgroup of UC patients in clinical remission who nevertheless have higher relapse risk, which could help personalize monitoring and care.

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Comorbidity Between Mood Disorders and Chronic Somatic Diseases, With a Focus on Cardiometabolic Disease, and Its Mechanistic Crosstalk.
Depression and anxiety

Comorbidity Between Mood Disorders and Chronic Somatic Diseases, With a Focus on Cardiometabolic Disease, and Its Mechanistic Crosstalk.

Mood disorders commonly co-occur with chronic somatic diseases, including IBD; understanding shared mechanisms may explain worse outcomes and suggest multidisciplinary care needs.

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Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.
Revista da Associacao Medica Brasileira (1992)

Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.

Fear of movement was more common and more severe in people with ulcerative colitis in this study. Addressing kinesiophobia could help increase physical activity and improve function and quality of life for people with...

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Disorders of Gut–Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.
American Journal of Gastroenterology

Disorders of Gut–Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.

DGBI-like symptoms are common in children whose IBD is biochemically quiescent and are associated with worse quality of life and more anxiety—issues that can affect daily functioning and disease management even when...

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Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.
The American journal of gastroenterology

Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.

Children with IBD can have persistent gut–brain interaction symptoms even when inflammation is quiescent; these symptoms are linked with worse quality of life and higher anxiety. Recognizing DGBI-like symptoms may help...

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Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.
Journal of psychosomatic research

Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.

Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues...

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Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial
Digestive Diseases and Sciences

Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial

Self‑management programs delivered by nurses may help people with IBD improve daily functioning, confidence in managing their condition, and quality of life even when inflammation markers don’t change. That matters...

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Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration.
Journal of clinical psychology

Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration.

Body-image concerns in IBD are linked with poorer mental health, eating behaviours, and overall quality of life. Understanding these experiences can help clinicians and support services better address emotional and...

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Microbiome-driven alterations in tryptophan metabolism contribute to behavioral comorbidities in the Muc2 knockout mouse model of chronic colitis.

IBD is increasingly linked with anxiety, depression, and cognitive symptoms; this study suggests gut microbes may change tryptophan metabolism in colitis and contribute to those brain-related symptoms, which could point...

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