ClinicalTrials.gov
Cure8 trial brief
A Mindfulness-based Stress Reduction Program for IBD
Mental health and quality of life
Anxiety
Depression
Flare
Clinical Trial Phase 1
Adult patients
Clinicians
Researchers
Why This Matters
Stress and psychological distress are common in people with IBD and may influence symptoms and inflammation. This trial tests whether an 8‑week MBSR program can improve psychological wellbeing and whether those benefits relate to measurable changes in inflammation and the gut microbiome.
Who Should Pay Attention
Adults with Crohn’s disease or ulcerative colitis; clinicians managing IBD mental‑health care or adjunct therapies; researchers interested in mindfulness interventions, biomarkers, or the microbiome.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment70 participants
Study statusNot_yet_recruiting
Source depthTrial registry record
What To Know
This is an interventional, open-label, comparator-controlled trial run by the Nova Scotia Collaborative IBD Program and listed as Not Yet Recruiting.
About 70 adults with mild-to-moderately active IBD will be randomized to either an 8‑week virtual MBSR course (weekly 2.5-hour sessions plus a day session and homework) or standard of care plus an educational stress‑reduction video.
The investigators plan to collect psychological questionnaires, clinical disease activity data, medication/surgical history, microbial diversity, and cytokine arrays to explore mental‑health and biological effects of MBSR on the brain–gut axis. The trial focuses on feasibility and mechanistic biomarkers rather than testing a new drug.
Keep In Mind
This is a registered interventional trial (Not Yet Recruiting) and does not contain outcome data. The study is relatively small and open‑label; biomarker and microbiome analyses are exploratory.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorNova Scotia Health Authority
Trial IDNCT07266883
Study typeInterventional
Trial phaseNA
Enrollment70 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedSep 8, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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