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Ulcerative colitis news across medications, symptoms, monitoring, procedures, research, access, and daily life.
Page 1 of 21 · 986 articles
This study describes a new oral peptide hydrogel that, in mouse models, appears to reduce colitis severity by acting on both immune signaling (TLR4) and the gut microbiome. For people with UC, treatments that target both...
New or late-stage drugs from a major company can change future treatment options and availability for people with IBD. J&J’s pipeline mentions several programs specifically targeting ulcerative colitis and Crohn’s...
Surveillance colonoscopies in IBD are meant to detect dysplasia or cancer; this report shows some solitary polyps may be benign retention polyps. Correct endoscopic removal and pathology spare patients from unnecessary...
Vitamin D deficiency was common among Albanian patients with IBD and showed a weak inverse association with disease activity in ulcerative colitis, suggesting vitamin D status may relate to symptom burden or...
This trial tests whether an oral S1P modulator (etrasimod) is more effective than standard mesalazine for inducing remission in adults with active UC — a question that could affect initial treatment choices in China.
This study will collect real-world data on etrasimod, an oral S1P receptor modulator, in people with ulcerative colitis, using patient-reported symptom measures over one year — information that may help patients and...
A pediatric Phase 2 trial testing etrasimod could expand treatment options for children with moderately to severely active ulcerative colitis if later shown safe and effective. Families of affected children and their...
The study identifies a molecular link between epithelial mitochondrial oxidative stress and NLRP3-driven inflammation in ulcerative colitis models, suggesting a possible new target for research into disease mechanisms...
Growth and nutrition are common concerns in children with IBD because poor weight gain and short stature can affect long‑term health and development.
Cure8 found this source from Journal of paediatrics and child health, but the page could not be read reliably yet. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. Open the original...
This paper explores whether individualized integrative management including traditional Chinese medicine might influence outcomes in patients with biologic‑refractory, surgery‑intended acute severe ulcerative colitis — a...
The study points to three bile-acid–related genes that may be linked to inflammation in ulcerative colitis and could serve as biomarkers or targets for future research into disease mechanisms and patient stratification.
The study links TXNIP/NLRP3 inflammatory signaling to disease features in an animal UC model and tests engeletin and rosuvastatin as interventions that lowered inflammatory markers—information relevant to researchers...
Colon-targeted delivery systems aim to concentrate drugs in the colon, which could improve effectiveness and reduce systemic side effects for IBD and colorectal cancer treatments. Understanding these approaches helps...
The study links activation of the cGAS–STING immune-sensing pathway to NF-κB–driven inflammation and tumor formation in UC models, which could help explain mechanisms behind colitis-associated colorectal cancer risk.
The work aims to predict relapse and personalize herbal maintenance dosing for UC, which matters because better risk stratification and tailored management could reduce relapses and avoid unnecessary treatment changes.
This animal study suggests date palm pollen extract reduced inflammation and tissue damage in a rat model of colitis, which could point to new lines of research into dietary supplements or natural compounds for gut...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and CRP. The original article is from Alimentary Pharmacology & Therapeutics.
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Crohn's disease, and Inflammatory bowel disease. The original article is from Alimentary Pharmacology &...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Community and awareness. The original article is from Iraqi Journal of Pharmacy.
The study links a common plant compound (oxalate) to higher stool levels and worse inflammation in IBD, suggesting diet and gut handling of oxalate could affect disease activity and that microbiome-targeted strategies...
This study reports a new herbal hydrogel designed to repair the intestinal barrier, shift gut microbes, and modulate immune signals (IL-22/IL-34) in preclinical models of ulcerative colitis—ideas that could inform future...
Adding a mesalazine retention enema to oral mesalazine improved short-term symptom relief and endoscopic signs of mucosal healing in mild-to-moderate left-sided ulcerative colitis in this retrospective study. That could...
Blood biomarkers that predict vedolizumab response could help patients and clinicians choose the most effective therapy sooner and avoid ineffective treatments. The study suggests LRG and MCP‑1 may differentiate...
If you have moderate–severe ulcerative colitis, this study suggests that typical phase III trials may exclude more than half of patients seen in specialty clinics, which can make trial results less representative of...
The paper identifies a potential microbiome–metabolite–PKC pathway by which an herbal formula reduced colonic injury in a rat model of UC; this could point to new targets for research into mucosal repair and...
People with ulcerative colitis may be interested because the study describes a natural compound that reduced inflammation and disease signs in a mouse model and acted through the gut microbiota and immune pathways —...
The study identifies miR-23b-3p as elevated in UC and CD and linked to disease severity, and shows in cell models that lowering miR-23b-3p can improve epithelial barrier function via Erbin. If confirmed, this miRNA could...
The study suggests a rice bran plus feruloyl-esterase–producing bacterium reduced inflammation and tissue injury in a mouse model of ulcerative colitis, pointing to a possible diet–microbiome approach worth further...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Food Bioscience.
A formulation that keeps budesonide at the colon surface longer and protects the mucosa could enhance topical treatment for ulcerative colitis and improve mucosal healing compared with standard enemas.
Perceived stigma may affect how Black people with IBD view their care and whether they stick with medications, which can influence disease management and outcomes. Understanding these links can point to targets for...
IBD-U means no clear Crohn’s or ulcerative colitis diagnosis yet — that uncertainty can affect treatment decisions and follow-up. The review highlights tests that may help clarify diagnosis and stresses that many...
People with UC often look for dietary supplements or ‘‘natural’’ add-ons. This review explains which nutraceutical approaches have the most and least clinical support, helping patients and clinicians weigh potential...
The paper links common tire-derived pollutants to intestinal injury and pathways also implicated in Crohn’s disease and ulcerative colitis, suggesting environmental chemicals could influence gut inflammation. If...
The study describes a mechanism by which Huaier granules reduced colitis-related inflammation in mice and cell models by targeting macrophage cGAS–STING signaling and altering the gut microbiome—information that could...
Pharmacokinetics affect how well biologic drugs work for IBD. Better PK data could help explain why many patients have inadequate responses and could inform personalized dosing for IL-23p19 inhibitors used in Crohn’s...
This paper explores whether polygenic risk scores (PRS) predict key long-term outcomes after IBD diagnosis — notably intestinal surgery — which could be relevant for risk stratification research and future clinical tools...
Prebiotics change how gut microbes ferment carbohydrates and produce metabolites that can affect gut health. For people with IBD, a prebiotic that is well fermented by their microbiota, increases beneficial bacteria and...
The work highlights a dietary polysaccharide that reduced inflammation and improved mucosal barrier function in a mouse colitis model through gut-microbiota changes — a mechanism relevant to IBD research and potential...
Early-onset IBD affects children worldwide and the commentary highlights that although deaths are declining, more children are living with IBD and social inequalities are widening — issues that can affect access to care,...
If you follow IBD research, this study suggests a heat-stabilized (nonviable) multi-strain bacterial product reduced inflammation and improved some disease measures in a mouse model of ulcerative colitis — a step that...
Regional data can reveal how IBD presents and behaves locally; that information helps clinicians with earlier recognition and tailoring care and helps researchers compare geographic phenotypes.
IBD patients can have lung involvement without symptoms. Simple spirometry focused on small-airway measures might help detect early pulmonary changes and prompt further evaluation or monitoring.
The study links worse UC activity with higher rates of anxiety and depression and with poorer quality of life among patients in Pakistan, suggesting mental-health screening could be relevant to overall disease...
People with UC face higher cardiovascular risk; this study links a specific ITGA4 genetic variant (rs1143674 CC) with subclinical atherosclerosis in UC patients over 40, which could help identify higher-risk individuals...
People with ulcerative colitis considering or taking ozanimod or etrasimod may want to know about potential adverse events reported after these drugs entered the market, especially for nervous‑system, eye, and cardiac...
The work links a specific post-transcriptional regulator (AUF1) to barrier dysfunction in UC and demonstrates that AUF1-restored organoids can enhance mucosal repair in mice, suggesting a possible new regenerative...
