Symptoms and disease activity

Abdominal Pain

Abdominal pain articles covering pain symptoms, flare signals, monitoring, and treatment context in Crohn's disease and IBD. Symptom context emphasizes flares, remission, daily disease activity, and patient-relevant warning signs.

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Long-term Benefits of Mirikizumab on Patient-Reported Outcomes in Individuals with Crohn's Disease: 2-Year Results from the VIVID-2 Extension Study.
Clinical and translational gastroenterology

Long-term Benefits of Mirikizumab on Patient-Reported Outcomes in Individuals with Crohn's Disease: 2-Year Results from the VIVID-2 Extension Study.

Patients and clinicians considering long-term use of mirikizumab for Crohn's disease may find evidence here that quality of life and common symptoms (fatigue, abdominal pain, stool frequency) can remain improved out to...

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Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
ClinicalTrials.gov

Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease

If gut microbes produce LPC/LPA that are linked to chronic abdominal pain, it could point to new biomarker or microbiome-targeted approaches for unexplained pain in IBD patients whose inflammation is quiet or minimal.

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Over‐the‐Counter Analgesics Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study Based on a New Questionnaire
Basic & Clinical Pharmacology & Toxicology

Over‐the‐Counter Analgesics Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study Based on a New Questionnaire

OTC painkiller use is very common among people with IBD, and those with recent disease activity are more likely to use them frequently and to take them specifically for IBD-related pain. Knowing this can help clinicians...

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Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Mymensingh medical journal : MMJ

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.

Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...

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Bidirectional Brain-Gut Signaling in the Persistence of IBS-like Symptoms in Inflammatory Bowel Disease
NIH RePORTER

Bidirectional Brain-Gut Signaling in the Persistence of IBS-like Symptoms in Inflammatory Bowel Disease

Many people with IBD have ongoing IBS-like symptoms despite little or no intestinal inflammation. This project targets brain–gut and autonomic mechanisms that might explain symptom persistence and tests a non-drug...

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Symptom-Based Hospitalization Risk Differs Between Ulcerative Colitis and Crohn’s Disease: A Nationwide Emergency Department Study
Bratislava Medical Journal

Symptom-Based Hospitalization Risk Differs Between Ulcerative Colitis and Crohn’s Disease: A Nationwide Emergency Department Study

The study suggests ED presentation symptoms predict admission differently in UC versus CD, which could affect triage and short-term risk assessment for IBD patients. Knowing which symptoms are stronger predictors by...

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Clinical features of intestinal tuberculosis: an analysis of 46 cases, including six initially misdiagnosed as Crohn's disease
Frontiers in Medicine

Clinical features of intestinal tuberculosis: an analysis of 46 cases, including six initially misdiagnosed as Crohn's disease

ITB can closely mimic Crohn’s disease, so this study is relevant because it describes diagnostic test yields and illustrates that targeted TB testing and therapeutic trials of antituberculosis treatment can help...

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Living well with Crohn’s & Colitis fatigue, pain and urgency/faecal incontinence: the IBD-BOOST research programme including an RCT
Europe PMC

Living well with Crohn’s & Colitis fatigue, pain and urgency/faecal incontinence: the IBD-BOOST research programme including an RCT

Many people with IBD experience persistent fatigue, pain and faecal incontinence even when inflammation is controlled; this programme tested a supported online self-management approach to help those symptoms and assessed...

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Optimism and mindfulness are associated with decreased abdominal pain among adolescents with inflammatory bowel disease.
Journal of the Canadian Association of Gastroenterology

Optimism and mindfulness are associated with decreased abdominal pain among adolescents with inflammatory bowel disease.

Adolescents with IBD often experience abdominal pain that affects daily life. This study suggests psychological resilience — especially optimism and mindfulness — is linked with less pain, pointing to nonpharmacologic...

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Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.
The American journal of gastroenterology

Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.

Children with IBD can have persistent gut–brain interaction symptoms even when inflammation is quiescent; these symptoms are linked with worse quality of life and higher anxiety. Recognizing DGBI-like symptoms may help...

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Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.
Journal of clinical medicine

Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.

This study describes how IBD presents and early outcomes in children at a tertiary center, noting high rates of inflammation, nutritional problems, and early flares. Findings may help families and clinicians understand...

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