Research topics
Single-cell sequencing articles covering cell atlases, RNA sequencing, gene activity, and high-resolution IBD research methods.
5 articles
If correct, the paper points to a previously underappreciated immune cell (GzmK+ tissue-resident CD8+ T cells) as a potential driver of Crohn’s inflammation — which could lead to new biomarkers or therapies that work...
Researchers mapped cell-type gene activity in Crohn’s ileum and found persistent immune-related gene activation in stem cells after inflammation healed, plus macrophage signatures tied to the JAK/STAT pathway. This could...
This study maps gene activity in over a million gut cells and finds lasting molecular changes in stem cells after inflammation, which could help explain recurrence and guide future research toward new drug targets.
The study maps cell types and signals linked to submucosal scarring in Crohn's disease, a complication without drug treatments that often requires surgery. Understanding these mechanisms could point to future therapeutic...
Research that maps neutrophil behavior in children with Crohn’s could reveal biological mechanisms and biomarkers relevant to disease progression or treatment response. Understanding neutrophil roles helps scientists...
