Procedures and surgery topics
Colectomy articles covering colon surgery, recovery, risks, ostomy or pouch decisions, and IBD surgical care. Procedure context emphasizes surgery, endoscopy, ostomy care, recovery, and follow-up monitoring.
35 articles
People hospitalized with acute severe ulcerative colitis face a high risk of steroid failure and need for rescue therapy or colectomy. This trial explores whether adding the JAK inhibitor tofacitinib to corticosteroids...
People with PSC who undergo liver transplant — especially those who have IBD at the time of transplant — remain at elevated risk for colorectal neoplasia, IBD flare or new-onset IBD, and for PSC recurrence. Knowing this...
This study looks directly at whether failing multiple biologic drugs before elective subtotal colectomy affects short-term surgical outcomes for people with ulcerative colitis — information that can help patients and...
Based on the title and source metadata, this appears to be a guideline related to Ulcerative colitis, Inflammatory bowel disease, and Colectomy. The original article is from Techniques in Coloproctology.
For people hospitalized with acute severe UC, the findings suggest that measuring early infliximab pharmacokinetics could help personalize rescue therapy and potentially reduce colectomy risk by identifying who may need...
The study suggests that using infliximab as first-line therapy (rather than IV corticosteroids) may produce more durable remission and reduce long-term colectomy risk in moderate-to-severe ulcerative colitis.
AMNs are rare but can be malignant and may mimic UC flares or appendicitis, which can delay diagnosis. For people with long-standing UC, awareness may prompt appropriate imaging and surgical referral.
This study reports real-world short-term outcomes after colectomy for IBD at a tertiary New Zealand centre, including complication rates and how often restorative surgery (ileal pouch) was later performed—information...
People with ulcerative colitis face long-term health risks beyond the gut. This study suggests that getting a colectomy early after diagnosis might be linked to lower long-term risk of cardiovascular disease and type 2...
Children with newly diagnosed IBD are increasingly started on advanced therapies early after diagnosis and are receiving fewer corticosteroids.
For people with UC who do not respond to tacrolimus, adding infliximab may induce remission and reduce the short-term need for colectomy. The findings point to a potential rescue strategy and an option to transition to...
The case links thymic hyperplasia, thyroid autoimmunity, and severe UC with colorectal neoplasia, suggesting possible shared immune dysregulation that might interest patients and clinicians, but it does not support...
This study directly compares two rescue medications used when intravenous steroids fail in acute severe ulcerative colitis, reporting similar short-term remission and safety but a slower early response with tacrolimus —...
A new oral investigational drug (TP317) is entering a Phase 1b study in adults with active UC to assess safety and pharmacokinetics, which may be relevant to patients seeking information about emerging therapies.
The analysis compares rescue drugs used when severe ulcerative colitis doesn't respond to IV steroids — a high-stakes situation where avoiding colectomy matters.
Surgery is still a core part of care for certain UC and Crohn's patients despite better medical therapies. Newer surgical techniques and coordinated medical–surgical approaches aim to reduce complications and recurrence...
Knowing a patient’s estimated infliximab clearance before starting rescue therapy for acute severe ulcerative colitis could help identify who may need higher or intensified induction dosing and who might be at greater...
For people with multi-refractory Crohn’s disease or ulcerative colitis, adding a JAK inhibitor to an existing biologic (advanced combination therapy) may convert partial responses into deeper remission in selected cases,...
Nutrition during acute severe ulcerative colitis matters because patients can become rapidly nutritionally fragile, and appropriate feeding and monitoring can affect recovery, complications, and readiness for surgery....
Patients with UC who fail both anti-TNF and JAK inhibitor therapies have limited options. This report suggests tacrolimus can be used as a short-term bridge or in combination to reach another maintenance drug, with many...
People with IBD and clinicians often face decisions about whether to stop biologics or small molecules before abdominal surgery.
For people hospitalized with acute severe ulcerative colitis, starting a JAK inhibitor together with IV steroids right away (rather than waiting for steroids to fail) could potentially control inflammation sooner and...
The T&W criteria are still used to define severe UC on admission, but relying on them alone may delay recognition of steroid non‑response and escalation decisions. Integrating biomarkers, endoscopy, and imaging can help...
This is relevant because a treatable infection (intestinal tuberculosis) can present like colorectal cancer or IBD and lead to emergency surgery. Recognizing it earlier could change management and avoid unnecessary...
This study addresses whether removing the appendix changes long-term UC outcomes. People with UC or their clinicians might expect surgery to alter disease course; these real-world data suggest it generally does not for...
The appendix in conventional UC appears to be inflamed early and then remodels to fibrous obliteration over decades, which could influence thinking about timing or rationale for appendectomy-based interventions.
If reliable, an earlier day‑3 PUCAI cutoff could help identify children with flare‑related ASUC who are unlikely to respond to IV steroids and who may benefit from earlier planning for second‑line therapy rather than...
For patients and clinicians facing steroid- and infliximab-refractory acute severe ulcerative colitis, upadacitinib may be a third-line medical option that can produce rapid symptom and CRP improvement and allow some...
The review examines whether removing the appendix could change the course of ulcerative colitis — a potential surgical option that might lower colectomy or hospitalization risk in some scenarios but also carries...
Lowering the CRP cutoff could help hospitals identify hospitalized UC patients at higher risk of needing surgery who are currently classified as less severe. That may affect monitoring and treatment decisions during...
Surgery is common in Crohn’s disease and different types of resections carry different short-term risks.
The report suggests adding acupuncture to anti-TNF therapy may improve short-term symptom control and mucosal healing and reduce early colectomy risk for a TCM-defined subgroup of ulcerative colitis patients, which could...
Shows real-world long-term outcomes in a large Chinese UC cohort and highlights that baseline disease activity predicts need for escalation and colectomy risk; points to opportunities to improve treat-to-target care.
People with ulcerative colitis who have had colectomy can rarely develop inflammation of the small intestine and high-output stomas that are hard to control.
GI perforation is a serious, potentially life-threatening complication that can occur in people with autoimmune diseases; this report highlights that perforation can happen during corticosteroid tapering and that careful...
