Cure8 research brief
AMNs are rare but can be malignant and may mimic UC flares or appendicitis, which can delay diagnosis. For people with long-standing UC, awareness may prompt appropriate imaging and surgical referral.
Clinicians (gastroenterologists, colorectal surgeons), researchers studying UC complications, and adult patients with long-standing ulcerative colitis
This paper reviewed 29 patients with UC and histologically confirmed AMNs. Most patients had long-standing UC and many had active colitis when AMNs were found. Presentations ranged from abdominal pain to incidental findings.
All patients underwent surgery, from appendectomy to colectomy/proctocolectomy, and pathology included benign cystadenomas, low-grade appendiceal mucinous neoplasm (LAMN), and mucinous adenocarcinoma. The authors emphasize preoperative imaging to assess extent and the need for definitive resection to reduce risks such as pseudomyxoma peritonei.
Findings are drawn from a small pooled set of case reports/series; the review is posted on Research Square (abstract/full-text available) and should be interpreted as summarizing rare events rather than defining population-level risks.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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