Pediatric surgery international
Cure8 research brief
Why This Matters
Colorectal lymphoma in children can mimic IBD flares or cause surgical emergencies; recognizing this can prevent inappropriate escalation of immunosuppression and speed correct diagnosis and treatment.
Who Should Pay Attention
Pediatric gastroenterologists, pediatric surgeons, clinicians treating children with IBD, parents and caregivers of pediatric IBD patients, and researchers in pediatric colorectal malignancy.
Study Snapshot
Story typeResearch paper
Evidence typeSystematic review
Source depthJournal abstract
What To Know
The review pooled recent case reports/series and found colorectal non-Hodgkin lymphoma in children can present like an IBD flare, colorectal carcinoma, bowel obstruction, or acute abdomen.
Some cases occurred in very young children and a few arose in the setting of inflammatory bowel disease or during treatment with biologics (one case noted while on vedolizumab).
Because lymphoma may be mistaken for IBD activity, the authors emphasize early endoscopic biopsy and imaging to avoid inappropriate escalation of immunosuppression and to guide staging and surgical planning.
Surgery is not the mainstay treatment for lymphoma but has an important role for tissue diagnosis and for managing complications such as perforation, obstruction, or intussusception; minimally invasive en-bloc resection was described as feasible in selected patients.
Keep In Mind
This entry is based on the article abstract (systematic review of recent case reports/series). The review highlights rare presentations and surgical implications but does not provide population-level incidence or treatment outcomes beyond case descriptions.
Source Details
Review the original publication for the complete reporting, methods, and context.
Systematic review
Evidence type derived from source or registry metadata.
PublicationPediatric surgery international
AuthorsAnit Joseph K, Shilpa Sharma
Study typeJournal article, systematic review
Indexed viaPubMed
Source typeResearch paper
PublishedJul 12, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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