Perforation

This study provides real-world evidence about using upadacitinib as a maintenance therapy in children with refractory Crohn’s disease — a group with limited treatment options.

This study gives real-world 52‑week data on upadacitinib maintenance in children with refractory Crohn's disease, showing meaningful remission rates but also notable adverse events. That balance is important for families...

Cocaine use can trigger severe GI problems that mimic common surgical and inflammatory conditions; recognizing the link can speed diagnosis and management. Most published evidence is low-level (case reports/series), so...

Stopping Crohn's medications can cause flares and serious complications, and restarting treatment may be slower or less effective. Adherence and financial or practical support can help prevent these harms.

Imaging can reveal characteristic bowel and vascular patterns that help distinguish Crohn's, UC, celiac disease, and systemic autoimmune or vasculitic causes of GI symptoms, which may speed diagnosis and detect dangerous...

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Perforation, and Complications. The original article is from Digestive diseases and sciences.

GI perforation is a serious, potentially life-threatening complication that can occur in people with autoimmune diseases; this report highlights that perforation can happen during corticosteroid tapering and that careful...

Colorectal lymphoma in children can mimic IBD flares or cause surgical emergencies; recognizing this can prevent inappropriate escalation of immunosuppression and speed correct diagnosis and treatment.

The story shows that emergency surgery and coordinated specialist care can treat life‑threatening Crohn’s complications and help patients regain daily activities. It highlights the role of reconstructive surgery and...

This is the first reported organoid-based intestinal regenerative therapy entering clinical trials, which could offer a new approach for Crohn’s patients whose ulcers don’t heal with current treatments. Early-stage...

Skin disease (hidradenitis suppurativa) may be more common in people with IBD—particularly Crohn disease—and could be linked with more severe intestinal complications. Awareness can prompt coordinated care between...