Diarrhea, abdominal pain, fatigue, bleeding, urgency, flares, remission, and symptom management news.
Page 2 of 9 · 398 articles
Patients with PsA and clinicians choosing long‑term biologic therapy may care about both durability of PsA control and safety signals for related inflammatory conditions like IBD and uveitis. This analysis reports...
People with IBD commonly experience mood disorders; identifying shared molecular signals could help explain why and point to biomarkers or targets for research. This study proposes three genes linked to conserved...
Depression is more common in people with Crohn’s and can worsen disease outcomes and quality of life. Recognizing and treating depression alongside Crohn’s may improve symptom control, reduce hospitalizations, and lower...
A simple blood marker (LBP) that reflects bacterial exposure across the gut barrier was linked to disease severity and immune activity at diagnosis and during follow-up—especially in ulcerative colitis—so it might help...
The study helps explain how granulomas—linked to more severe Crohn’s disease—might form by repurposing lymphoid follicle macrophages, pointing to cellular programs and signals that could be relevant for future biomarkers...
If local norepinephrine promotes neutrophil‑driven inflammation in UC, that could help explain disease progression in some patients and point to biomarkers (ADRB2‑rich neutrophils) that might predict response to anti‑TNF...
STAT3 is a central immune signaling molecule implicated in ulcerative colitis; understanding its dual roles could influence future biomarker research and therapies for UC. The review highlights why STAT3’s...
Faecal urgency is a frequent, disabling symptom in Crohn's disease that was common in this cohort and tied to poorer quality of life, mental-health burden, and more healthcare use over one year.
Based on the title and source metadata, this appears to be a clinical study related to Irritable bowel syndrome, Abdominal Pain, and Symptoms and flares. The original article is from hmpgloballearningnetwork.com.
The study identifies an epithelial cell death signature (necroptosis then apoptosis) that appears before major inflammation and which correlated with relapse over 24–36 months, suggesting a possible early biomarker to...
Extraintestinal problems are common in IBD and can cause significant symptoms and treatment needs beyond the bowel. Knowing their frequency helps patients and clinicians prioritize screening and multidisciplinary care.
Cure8 found this source from health.usnews.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. Open the original article for the full...
People with IBD often have sleep problems and ongoing inflammation; melatonin could help both sleep and clinical disease activity, which may improve quality of life. The review suggests potential benefit but is not...
Emotional functioning and parent-child mental health are linked with anxiety, depression, and quality of life in children with IBD and other GI autoimmune disorders. Identifying these issues may help families get...
First-person accounts of Crohn's or colitis can help others recognize severe symptoms, the emotional toll of chronic gut disease, and that surgery can be part of a pathway to symptom relief for some people.
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease, Vedolizumab, and Anti Integrin. The original article is from Journal of the Canadian Association of...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease, Irritable bowel syndrome, and Symptoms and flares. The original article is from Frontiers in...
The study links T cell metabolism and epigenetics to inflammation in IBD, highlighting GSK3β as a possible drug target. That could guide future therapies aimed at dampening pathogenic T cells in Crohn’s disease.
Microscopic colitis can cause chronic watery diarrhea yet have a normal-looking colon at endoscopy, so diagnosis is often delayed — even in younger adults. Recognizing this may lead to earlier biopsy and treatment.
If oxalate in certain plant foods can irritate inflamed intestines or be less well absorbed in IBD, eating large amounts could worsen symptoms for some patients. Awareness can help people track triggers rather than...
For people with Crohn’s disease, this study suggests that biologic drugs reduce inflammation in both proximal and distal small bowel to a similar degree, as measured by capsule endoscopy.
Persistent bowel symptoms can signal a range of conditions, including rare cancers; prompt evaluation helps ensure appropriate diagnosis and treatment. The story highlights symptom overlap between Crohn’s disease and...
Bowel urgency is a common, distressing symptom in ulcerative colitis that matters for quality of life. This analysis indicates vedolizumab may reduce urgency and that early improvement is linked to better clinical and...
The review proposes S100B as a molecular link connecting enteric glial activation, intestinal barrier dysfunction, and liver/brain inflammation. If confirmed, this could help explain symptom overlap between gut and...
Early, easily available blood markers that predict mucosal healing could help clinicians decide sooner whether a new or intensified therapy is working, potentially reducing prolonged ineffective treatment and guiding...
Personal stories can show how severe and disruptive Crohn’s symptoms can be, and that diagnosis may take time. The account also reinforces that Crohn’s is chronic and may require ongoing medical treatment plus lifestyle...
New biomarkers and cell-type insights could help future diagnostic tools or targeted therapies in UC by pointing to TRP channel–related genes and B/plasma cell involvement.
The study links a common compound in plant foods (oxalate) to intestinal inflammation in IBD, suggesting diet and oxalate metabolism may be modifiable contributors to flares.
Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Symptoms and flares. The original article is from Clinical and experimental dermatology.
Researchers increasingly implicate innate lymphoid cells in IBD inflammation and mucosal barrier breakdown — findings that could guide future diagnostics or therapies. For patients, this helps explain research directions...
Shortening ustekinumab dosing intervals raised drug levels and was associated with high rates of steroid-free clinical remission in this small prospective IBD cohort, offering a practical option for patients who lose...
If gut microbes produce LPC/LPA that are linked to chronic abdominal pain, it could point to new biomarker or microbiome-targeted approaches for unexplained pain in IBD patients whose inflammation is quiet or minimal.
A trained singer with Crohn's disease showed cyclical vocal changes tied to biologic infusion timing — this could affect quality of life and work for voice-dependent people with IBD.
OTC painkiller use is very common among people with IBD, and those with recent disease activity are more likely to use them frequently and to take them specifically for IBD-related pain. Knowing this can help clinicians...
The work suggests specific host genes and cell types that might mediate links between gut microbes and IBD, which could direct future laboratory research into mechanisms and potential biomarkers.
Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...
Phase angle, an easy-to-measure BIA parameter, was lower in IBD patients with malnutrition and higher disease activity. Detecting malnutrition earlier could matter for patients' strength, healing, and overall outcomes.
The paper identifies subtype-specific changes in enteric glial cells and mast cell activity in microscopic colitis and shows some treatment-associated reductions after budesonide; that helps explain disease biology and...
If you or your clinician are considering switching from IV to subcutaneous vedolizumab, this multicentre cohort suggests most patients (about 84%) remain on the subcutaneous formulation at one year. The switch appears...
Fatigue markedly affects quality of life for people with Crohn’s and often remains after inflammation is controlled. Recognizing multiple drivers — psychological distress and immune/hematologic signals — could change how...
Cure8 found this source from jo24.net, but the page could not be read reliably yet. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Symptoms and flares. Open the original article for the full...
Cure8 found this source from health.usnews.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. Open the original article for the full...
People with IBD in remission commonly continue to have IBS-like symptoms; this review summarizes randomized trial evidence for symptom-directed treatments and finds no definitive best option.
The study suggests active smoking reduces the effectiveness of anti-TNF biologics in people with IBD, which could affect treatment response and the need to switch or escalate therapies. This supports including smoking...
If you have UC, bowel urgency may indicate active inflammation more reliably than some other symptoms. Recognizing urgency could help prompt timely objective testing and treatment decisions.
Researchers used clustering on mixed clinical and treatment data to identify distinct Crohn's disease course trajectories and a small high-burden subgroup. If validated, such trajectories might help inform prognosis and...
Persistent diarrhea is a common, quality-of-life–limiting problem in ulcerative colitis; this review synthesizes how epithelial transport, barrier damage, immune signaling, mitochondria, and microbiota interact and...
A direct-vision push-type dilator (BougieCap) was used to safely dilate a low rectal stricture from Crohn's disease, allowing same-session sigmoidoscopy and biopsy and reported symptom improvement up to 18 months.
