Complication topics
Articles tagged with Primary Sclerosing Cholangitis in the complications topic, grouped for easier browsing of related complication research and patient-relevant updates.
7 articles
PSC is closely linked with IBD (especially ulcerative colitis); understanding mechanisms that damage bile ducts could point to new future therapies or biomarkers.
People with IBD and coexisting primary sclerosing cholangitis (PSC) may get faecal calprotectin tests to monitor colon inflammation. If PSC raises FC independently of colitis, FC could mislead decisions about IBD...
Itch is a frequent, often severe symptom in PSC that is linked to liver disease severity and worse quality of life. Recognizing and measuring pruritus matters because it significantly affects daily functioning and may...
If you have PSC-IBD or care for someone who does, this study suggests the gut microbiota and its ability to make secondary bile acids may help drive inflammation and colorectal dysplasia risk.
PSC occurring with IBD changes cancer risk and surveillance needs: patients can have extensive but asymptomatic colitis and a higher colorectal and biliary cancer risk. The review outlines gaps in diagnosis, monitoring,...
This case report describes successful use of vedolizumab to treat severe UC in a patient who also had PSC and SLE — a rare and complex combination. Patients and clinicians may find it relevant when considering biologic...
PSC is rare in the general population but substantially more common in people with IBD, particularly ulcerative colitis, and it raises long-term hepatobiliary risks including cholangiocarcinoma—so knowing how often PSC...
