Complication topics
Articles tagged with Primary Sclerosing Cholangitis in the complications topic, grouped for easier browsing of related complication research and patient-relevant updates.
16 articles
A reusable transcriptomic atlas could let researchers compare new IBD biopsy datasets to a common reference, improving cross-study comparisons and helping separate inflammation from persistent disease-state biology that...
People with IBD and coexisting primary sclerosing cholangitis (PSC) are at higher colorectal neoplasia risk and may respond differently to IBD medicines. This meta-analysis compiles available evidence on commonly used...
Extraintestinal problems are common in IBD and can cause significant symptoms and treatment needs beyond the bowel. Knowing their frequency helps patients and clinicians prioritize screening and multidisciplinary care.
PSC co-occurring with celiac disease appears more common than expected and is associated with a high rate of liver complications (including cirrhosis) and frequent coexisting IBD—information that may affect monitoring...
FibroScan detects liver fibrosis and steatosis that are common and sometimes under-recognized in people with IBD; identifying liver disease earlier could change monitoring or referral decisions, especially for patients...
VEO-IBD often presents with severe, extensive disease and can include monogenic causes and early hepatobiliary complications; knowing common presentations and early management patterns helps families and clinicians plan...
PSC — a serious bile-duct disease linked to IBD — was found on MRCP in about 1 in 10 people at IBD diagnosis, often without abnormal liver blood tests. Early radiological detection could affect monitoring and specialist...
People with IBD have higher risk of several GI and hepatobiliary cancers; imaging is an important complement to endoscopic surveillance for detecting cancers that may be transmural or outside endoscopic reach.
PSC frequently occurs with IBD and has unclear origins; understanding a shared glandular mechanism could help explain the link and point to new research targets relevant to both liver and colon disease.
PSC is closely linked with IBD (especially ulcerative colitis); understanding mechanisms that damage bile ducts could point to new future therapies or biomarkers.
People with IBD and coexisting primary sclerosing cholangitis (PSC) may get faecal calprotectin tests to monitor colon inflammation. If PSC raises FC independently of colitis, FC could mislead decisions about IBD...
Itch is a frequent, often severe symptom in PSC that is linked to liver disease severity and worse quality of life. Recognizing and measuring pruritus matters because it significantly affects daily functioning and may...
If you have PSC-IBD or care for someone who does, this study suggests the gut microbiota and its ability to make secondary bile acids may help drive inflammation and colorectal dysplasia risk.
PSC occurring with IBD changes cancer risk and surveillance needs: patients can have extensive but asymptomatic colitis and a higher colorectal and biliary cancer risk. The review outlines gaps in diagnosis, monitoring,...
This case report describes successful use of vedolizumab to treat severe UC in a patient who also had PSC and SLE — a rare and complex combination. Patients and clinicians may find it relevant when considering biologic...
PSC is rare in the general population but substantially more common in people with IBD, particularly ulcerative colitis, and it raises long-term hepatobiliary risks including cholangiocarcinoma—so knowing how often PSC...
