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Pregnancy and fertility

Pregnancy, fertility, lactation, family planning, and reproductive health news for IBD.

Page 1 of 2 · 61 articles

Subcutaneous infliximab in inflammatory bowel disease: from pharmacokinetic principles to clinical practice.
Expert opinion on biological therapy

Subcutaneous infliximab in inflammatory bowel disease: from pharmacokinetic principles to clinical practice.

A subcutaneous option for infliximab could simplify maintenance therapy, reduce infusion visits, and change how drug levels and accompanying immunomodulators are managed — issues many people with IBD and their clinicians...

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Contraception Among Women with Selected Autoimmune Diseases in the United States, 2019: A Claims Analysis.
PubMed

Contraception Among Women with Selected Autoimmune Diseases in the United States, 2019: A Claims Analysis.

Many reproductive-aged women with IBD and other autoimmune conditions may not have documented claims for prescription or permanent contraception, including women taking medications with potential fetal risks. That gap...

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Peripartum mental illness in serial pregnancies in mothers with multiple sclerosis and other chronic diseases.
Multiple sclerosis (Houndmills, Basingstoke, England)

Peripartum mental illness in serial pregnancies in mothers with multiple sclerosis and other chronic diseases.

Mothers with chronic diseases such as MS and IBD appear to have higher rates of peripartum mental illness requiring care across serial pregnancies, so awareness and monitoring during and between pregnancies may be...

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Evaluating embryo euploidy among patients diagnosed with inflammatory bowel disease undergoing in vitro fertilization.
Minerva obstetrics and gynecology

Evaluating embryo euploidy among patients diagnosed with inflammatory bowel disease undergoing in vitro fertilization.

People with IBD often worry whether their disease affects fertility or embryo health. This study directly looks at embryo chromosomal normality during IVF and found similar euploidy rates in patients with and without...

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Comprehensive Assessment of medication Risk-bEnefit in autoimmune disease for Healthy Pregnancies (CARE-HP)
NIH RePORTER

Comprehensive Assessment of medication Risk-bEnefit in autoimmune disease for Healthy Pregnancies (CARE-HP)

Pregnant people with IBD or other autoimmune diseases often face tough choices about continuing biologics or JAK inhibitors. CARE-HP aims to produce broader, disease-specific evidence to help patients and clinicians...

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Pregnancy safety of biologics in inflammatory bowel disease: A systematic review and network meta-analysis.
Therapeutic advances in gastroenterology

Pregnancy safety of biologics in inflammatory bowel disease: A systematic review and network meta-analysis.

People with IBD often need biologic therapy during their reproductive years. This review compiles comparative evidence about pregnancy risks with different biologics to inform decisions about continuing or switching...

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Hormonal contraception is not associated with recurrent flares in ulcerative colitis: a longitudinal time-dependent analysis
Inflammatory Bowel Diseases

Hormonal contraception is not associated with recurrent flares in ulcerative colitis: a longitudinal time-dependent analysis

Many women with UC use hormonal contraception and worry it might worsen disease activity. This study provides evidence that HCT was not linked to more recurrent flares or higher cumulative inflammatory burden in the...

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Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study
PubMed Central

Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study

This helps people with IBD and their care teams make delivery plans: if perianal disease is not active, having IBD alone was not linked to higher perineal injury risk in first-time vaginal births in this study.

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A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
ClinicalTrials.gov

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

People with IBD who are breastfeeding and are taking guselkumab may want data on how much of the drug gets into breast milk and the estimated infant exposure. This study aims to provide those measurements for the Q4W and...

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Beyond the drug maze: Ustekinumab in ulcerative colitis for a successful pregnancy
Adesh University Journal of Medical Sciences & Research

Beyond the drug maze: Ustekinumab in ulcerative colitis for a successful pregnancy

People with UC who need biologic therapy during conception or pregnancy often face limited evidence about safety and effectiveness; this case suggests ustekinumab may be an option when other drugs fail or are stopped for...

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
ClinicalTrials.gov

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Combining a UC biologic (mirikizumab) with a weight-loss drug (tirzepatide) could address both intestinal inflammation and excess weight, which may be important for people with moderately to severely active ulcerative...

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