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Pregnancy and fertility

Pregnancy, fertility, lactation, family planning, and reproductive health news for IBD.

43 articles

Hormonal contraception is not associated with recurrent flares in ulcerative colitis: a longitudinal time-dependent analysis
Inflammatory Bowel Diseases

Hormonal contraception is not associated with recurrent flares in ulcerative colitis: a longitudinal time-dependent analysis

Many women with UC use hormonal contraception and worry it might worsen disease activity. This study provides evidence that HCT was not linked to more recurrent flares or higher cumulative inflammatory burden in the...

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Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study
PubMed Central

Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study

This helps people with IBD and their care teams make delivery plans: if perianal disease is not active, having IBD alone was not linked to higher perineal injury risk in first-time vaginal births in this study.

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A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
ClinicalTrials.gov

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

People with IBD who are breastfeeding and are taking guselkumab may want data on how much of the drug gets into breast milk and the estimated infant exposure. This study aims to provide those measurements for the Q4W and...

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Beyond the drug maze: Ustekinumab in ulcerative colitis for a successful pregnancy
Adesh University Journal of Medical Sciences & Research

Beyond the drug maze: Ustekinumab in ulcerative colitis for a successful pregnancy

People with UC who need biologic therapy during conception or pregnancy often face limited evidence about safety and effectiveness; this case suggests ustekinumab may be an option when other drugs fail or are stopped for...

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
ClinicalTrials.gov

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Combining a UC biologic (mirikizumab) with a weight-loss drug (tirzepatide) could address both intestinal inflammation and excess weight, which may be important for people with moderately to severely active ulcerative...

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Genetic risk factor for Crohn's disease influences natural microbiome changes during pregnancy, mouse study finds
medicalxpress.com

Genetic risk factor for Crohn's disease influences natural microbiome changes during pregnancy, mouse study finds

This study suggests a Crohn's genetic risk factor can change pregnancy-related gut microbiome shifts and increase inflammatory signals in mice — which could help researchers look for microbial biomarkers that predict...

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