Seton

Perianal fistulas are a serious, common complication of Crohn's disease that are often difficult to heal. This study tests a real-world combination of surgery plus an approved IL-23 inhibitor (mirikizumab) to see if...

Perianal fistulas in Crohn’s disease are hard to treat and preserving continence is important. Long-term data suggesting laser ablation can achieve sustained healing in some patients are relevant for treatment decisions.

Anal fistulas are a common and often painful complication of Crohn’s disease that usually need medical or surgical treatment. Managing the underlying Crohn’s with biologic therapy is often necessary for fistulas to heal....