Nutrition in Clinical Practice
Cure8 research brief
Why This Matters
Malnutrition was common in this group and linked to lower fistula healing and a higher chance of needing proctectomy or abdominal surgery — outcomes that matter to people with perianal Crohn’s disease.
Who Should Pay Attention
Adults with perianal fistulizing Crohn’s disease, gastroenterologists, colorectal surgeons, nutritionists/dietitians, and caregivers involved in surgical planning or preoperative care.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This study looked back at medical records of 64 adults with perianal fistulizing Crohn’s disease treated with seton placement to see whether malnutrition affected outcomes. Using Nutrition Risk Screening‑2002 and GLIM criteria, 26.6% met criteria for malnutrition.
Those patients had lower albumin and hemoglobin, higher disease activity scores, lower rates of fistula healing, and were more likely to need proctectomy or abdominal surgery. After adjusting for other factors, malnutrition remained associated with a higher odds of proctectomy.
The report is an observational, retrospective cohort from two centers covering 2010–2022; it identifies malnutrition as a risk marker linked to worse surgical outcomes rather than proving causation. The methods and statistical associations are summarized in the abstract but Cure8 has not reviewed the full paper beyond the provided abstract.
If you or someone you care for has perianal Crohn’s and is undergoing seton placement, this study suggests clinicians may consider assessing and addressing nutritional status as part of overall care planning. It does not provide specific nutritional interventions or show that treating malnutrition will change outcomes.
Keep In Mind
This is a multicenter retrospective study (2010–2022) reported in an abstract form. Associations do not prove causation; the study identifies malnutrition as a clinical risk marker but does not test whether nutritional interventions reduce the risk of surgery. Details on interventions, timing, or long‑term follow up are not provided in the abstract.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationNutrition in Clinical Practice
AuthorsBruno Augusto Alves Martins, Oswaldo de Moraes Filho, Tuane Colles +5 more
InstitutionUniversidade de Brasília
Study typeArticle
Indexed viaOpenAlex
Source typeResearch paper
PublishedSep 22, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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