Adding a mesalazine retention enema to oral mesalazine improved short-term symptom relief and endoscopic signs of mucosal healing in mild-to-moderate left-sided ulcerative colitis in this retrospective study. That could...

CT-detected terminal ileitis was due to Crohn’s disease in only a small minority (12.5%) of cases in this cohort, so most patients with this imaging finding will need further testing to determine the cause.

Blood biomarkers that predict vedolizumab response could help patients and clinicians choose the most effective therapy sooner and avoid ineffective treatments. The study suggests LRG and MCP‑1 may differentiate...

If you have moderate–severe ulcerative colitis, this study suggests that typical phase III trials may exclude more than half of patients seen in specialty clinics, which can make trial results less representative of...

The paper identifies a potential microbiome–metabolite–PKC pathway by which an herbal formula reduced colonic injury in a rat model of UC; this could point to new targets for research into mucosal repair and...

People with IBD may be interested because the review summarizes biological pathways that could link gut inflammation to brain changes seen in Alzheimer’s disease, suggesting possible shared mechanisms and future research...

Comparative real-world data may help patients and clinicians weigh expected benefits and risks of risankizumab versus ustekinumab in Crohn’s disease, including effects on steroid-free remission and fistula healing.

Early-onset IBD affects children worldwide and the commentary highlights that although deaths are declining, more children are living with IBD and social inequalities are widening — issues that can affect access to care,...

If you follow IBD research, this study suggests a heat-stabilized (nonviable) multi-strain bacterial product reduced inflammation and improved some disease measures in a mouse model of ulcerative colitis — a step that...

A blood biomarker that reliably distinguishes UC from CD could help when endoscopy or histology are inconclusive and improve diagnostic confidence. This paper reports a candidate autoantibody (anti‑integrin αvβ6) with...

This study suggests that using 5‑ASA drugs early in children with Crohn’s disease was common but linked to more steroid use, delayed biologic treatment, and lower biologic durability — outcomes that matter for long‑term...

Diet appears both to influence IBD risk and to be a potential treatment component; patients may be able to reduce inflammation and support therapy through targeted dietary approaches. Clinicians and policymakers could...

Cure8 found this source from Gut, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Research and clinical trials. Open the original article for the full details.

People with IBD often face mental-health challenges, stigma and unpredictability of symptoms. Adapting an established CBT-based digital programme with direct input from patients and clinicians can make the content more...

Effective nursing-led support during clinical trial participation may improve engagement, adherence, retention, and timely symptom reporting for people with IBD. That could make trials safer, fairer, and more reliable...

The study presents a novel nanomaterial approach that aims to protect both inflamed intestines and kidneys by restoring intestinal barrier function and microbiome balance—mechanisms relevant to IBD-related systemic...

People with IBD and coexisting primary sclerosing cholangitis (PSC) may get faecal calprotectin tests to monitor colon inflammation. If PSC raises FC independently of colitis, FC could mislead decisions about IBD...

NUDT15 variants strongly affect how people metabolize thiopurine drugs used in IBD; knowing variant frequency helps decide whether routine pre-treatment genotyping is useful in Iran and among specific ethnic groups.

The study links changes in gut microbes and microbial functions with disease activity in children with IBD, suggesting the microbiome may play a role in recovery and could be a target to help sustain remission.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Complications. The original article is from Indian dermatology online journal.

Automated, annotation‑efficient lesion segmentation could speed image review and reduce labeling costs for Crohn’s disease imaging research and tool development. If robust, it may help create better AI tools to support...

Regional data can reveal how IBD presents and behaves locally; that information helps clinicians with earlier recognition and tailoring care and helps researchers compare geographic phenotypes.

Perianal fistulas are a common and morbid complication of Crohn's disease in children; a reliable, less burdensome imaging tool could help assess severity and monitor response to therapy more often than MRI.

This model could improve how researchers study IBD inflammation and early colorectal cancer in a human-derived, multicellular system that reproduces neuromuscular function and immune responses. That may speed preclinical...

The study presents a novel probiotic-based delivery system that targets both intestinal inflammation and anxiety/depression through the gut–brain axis, a potentially relevant concept for people with IBD who commonly...

CVID-related enteropathy can resemble celiac disease or IBD, carries high morbidity and mortality, and often does not respond to standard immunoglobulin therapy — patients and clinicians need awareness of its distinct...

The paper identifies a gut microbiome–driven pathway (flagellin → TLR5 → IL-15 → ARA) that might link intestinal microbial changes to systemic inflammation seen in long COVID and other immune-mediated diseases,...

Improving nursing support during IBD trial pathways could help people stay engaged, understand what participation involves, and report problems earlier—potentially making trials safer and more equitable.

IBD patients can have lung involvement without symptoms. Simple spirometry focused on small-airway measures might help detect early pulmonary changes and prompt further evaluation or monitoring.

An Expression of Concern signals potential problems with a preclinical IBD study’s data or images. Patients and clinicians should be cautious about relying on that specific animal-study finding when considering...

This paper explores whether polygenic risk scores (PRS) predict key long-term outcomes after IBD diagnosis — notably intestinal surgery — which could be relevant for risk stratification research and future clinical tools...

Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Complications. The original article is from cureus.com.

Based on the title and source metadata, this appears to be a patient education related to Community and awareness. The original article is from wlfi.com.

Behavioral coaching targets daily functioning, self-management, and psychological distress that often persist despite controlled inflammation — issues many people with IBD care about.

Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease and Research and clinical trials. The original article is from JCC Plus.

The study identifies a specific bacterial protein (OmpA) on probiotic-derived vesicles that reduced inflammation in a mouse colitis model by inhibiting TLR4/NF-κB signaling and improving barrier function, suggesting a...

Capsule endoscopy can safely help diagnose small-bowel disease in very young children, including cases of suspected IBD, and may be particularly helpful when blood tests or imaging suggest inflammation or low albumin....

AI chatbots are increasingly used for health information. If chatbot answers about IBD nutrition are inaccurate or hard to read, patients could be confused or misinformed. This study assesses those risks for ChatGPT-3.5.

Faster, more accurate chart abstraction could speed IBD research and quality monitoring while reducing reviewer workload and errors, which may help registries and studies that rely on manually curated EHR data.

This study suggests that circulating monocytes in newly diagnosed Crohn’s disease are transcriptionally and epigenetically reprogrammed toward inflammatory behaviour before they reach the gut, which could help explain...

Prebiotics change how gut microbes ferment carbohydrates and produce metabolites that can affect gut health. For people with IBD, a prebiotic that is well fermented by their microbiota, increases beneficial bacteria and...

The work highlights a dietary polysaccharide that reduced inflammation and improved mucosal barrier function in a mouse colitis model through gut-microbiota changes — a mechanism relevant to IBD research and potential...

Noninvasive intestinal ultrasound with superb microvascular imaging (SMI) may help predict the presence and size of endoscopic ulcers in the terminal ileum of people with Crohn’s disease. That could improve noninvasive...

This preclinical study suggests a plant-derived polysaccharide (THP) can repair the gut vascular barrier and reduce inflammation in experimental colitis via the S1P/S1PR2 pathway, pointing to a novel potential target for...

Understanding how different forms of programmed cell death in the gut lining contribute to barrier loss and inflammation could point to new therapeutic targets for IBD. The review also flags natural products and...

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Infliximab, and Upadacitinib. The original article is from Medicina clinica.

Early lab research suggests Aloe vera components may reduce intestinal inflammation and support mucus barrier repair in a zebrafish model, which could guide future IBD research on plant-derived therapies.

Changes in SKYRIZI’s dosing or approval for a subcutaneous induction option in Crohn’s disease could affect how the drug is delivered and accessed. AbbVie’s acquisition strategy may broaden future treatment options but...