Cure8

Why This Matters

New long‑term and real‑world data for risankizumab and upadacitinib were presented at ACG 2026, which may influence treatment considerations for people with difficult‑to‑treat Crohn's disease and ulcerative colitis.

Who Should Pay Attention

Adults with Crohn's disease or ulcerative colitis (especially those on or considering biologics/JAK inhibitors), gastroenterologists, and IBD researchers.

Study Snapshot

Story typeResearch news
Evidence typeConference abstract
Source depthFull source text

What To Know

AbbVie reported AFFIRM Phase 3 induction data for risankizumab in advanced therapy–naïve Crohn's disease and long-term findings from FORTIFY and SEQUENCE open‑label extension studies showing sustained clinical and endoscopic outcomes through multiple years of treatment.

The company also shared real‑world analyses for upadacitinib (RINVOQ) in difficult‑to‑treat Crohn's populations (fistulizing, stricturing, isolated ileal disease) reporting clinical and endoscopic response/remission rates in treated cohorts.

Keep In Mind

The article reports company announcements and conference abstracts; peer‑reviewed publications or full trial reports are needed to fully evaluate efficacy and safety claims.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Conference abstract Article type assigned from Cure8 classification; confirm details in the original source.
Publicationrttnews.com
AuthorsGayathry Prakash
Indexed viaGoogle News
Source typeWeb article
PublishedOct 12, 2026, 5:38 AM
Content availableFull source text

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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