The open respiratory medicine journal
Cure8 research brief
Why This Matters
Extraintestinal lung involvement can occur in IBD and patients often ask whether anti‑TNF drugs affect lung function; this small study found only minor changes in lung volumes and diffusion over short follow‑up in mostly mild IBD.
Who Should Pay Attention
Adult IBD patients on or considering anti‑TNF therapy; gastroenterologists and pulmonologists managing extraintestinal manifestations.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This abstract reports a small clinical study that measured lung function (body plethysmography including DLCO SB) in 32 IBD patients before and at least 6 weeks after starting anti‑TNFα therapy.
Overall FEV1 and vital capacity were within normal limits, residual volume (RV) was moderately elevated at baseline and showed a small decrease during therapy, while diffusion capacity (DLCO SB) was slightly reduced at baseline and decreased a bit further during therapy.
The authors conclude that anti‑TNFα therapy produced only slight changes in lung function parameters in this largely mild IBD cohort.
Keep In Mind
Small sample (n=32), short follow‑up (≥6 weeks), and mostly mild IBD limit generalizability. Source is an abstract-level journal record; results should be interpreted cautiously.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationThe open respiratory medicine journal
AuthorsSchulze M, Schulze B, Moog G +2 more
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedMay 25, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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