ACG Case Reports Journal
Cure8 research brief
Why This Matters
Persistent ulcers during apparent clinical remission can signal a coexisting infection rather than refractory Crohn’s inflammation; identifying Histoplasma changed management in this case.
Who Should Pay Attention
Clinicians treating Crohn’s disease, gastroenterologists, and patients on biologic therapy
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
The report highlights that persistent endoscopic ulceration in IBD can reflect dual pathology — ongoing Crohn’s inflammation plus an occult infection. In this case, fungal organisms were visible on special staining after repeat biopsy, prompting antifungal treatment alongside continued ustekinumab.
Keep In Mind
Single-case report based on abstract-level extraction; not evidence of common occurrence. Histoplasmosis is uncommon in immunocompetent hosts, so local epidemiology and clinical context matter.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationACG Case Reports Journal
AuthorsJorge Pacheco Oliva, Ninoska Meléndez Rodríguez, Abel Sánchez +1 more
InstitutionRoosevelt Hospital
Study typeArticle
Indexed viaOpenAlex
Source typeResearch paper
PublishedSep 25, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
Small Intestinal Extranodal Marginal Zone Lymphoma Mimicking Crohn's Disease.
Because intestinal lymphoma can closely mimic Crohn’s disease, recognizing red flags (severe malabsorption, proximal small-bowel involvement, monoclonal gammopathy, poor response to IBD therapy) can change diagnosis and...
Capsule retention in Crohn's disease requiring surgical management: two case reports.
Capsule endoscopy can be helpful for small-bowel assessment in Crohn’s disease but carries a risk of retention when strictures are present. Retained capsules may be asymptomatic yet still require surgery, so better...
Intestinal endometrosis mimicking Crohn's disease: a rare cause of nonspecific abdominal pain.
Cure8 found this source from Endokrynologia Polska, but the page could not be read reliably yet. It is tagged for Crohn's disease, Abdominal Pain, and Tests and monitoring. Open the original article for the full details.