Cure8

Why This Matters

Conference analyses describe how subcutaneous infliximab performs after stopping IV treatment and when compared with IV infliximab for ileal/ileocolonic Crohn's — information that could affect treatment decisions for patients and clinicians.

Who Should Pay Attention

Patients on or considering infliximab (including those switching from IV to subcutaneous), gastroenterologists and IBD clinicians, and researchers studying biologic formulations and biomarkers in IBD.

Study Snapshot

Story typeResearch news
Evidence typeClinical study
Source depthFull source text

What To Know

Celltrion will present two new analyses at ACG 2026: a post-hoc look at patients who restarted subcutaneous infliximab after an interruption in intravenous therapy, and a pooled, propensity-matched comparison of subcutaneous versus intravenous infliximab in ileal/ileocolonic Crohn's disease.

The interruption analysis evaluated prior anti-drug antibody status, timing between last IV dose and restart of subcutaneous therapy, and tracked clinical response, serum drug levels, fecal calprotectin, and CRP over time.

The pooled Crohn's analysis compared clinical remission and endoscopic outcomes at Week 54 between matched groups receiving subcutaneous versus IV infliximab.

Keep In Mind

Presentations are analyses to be delivered at ACG 2026; they appear to be post-hoc and pooled/propensity-matched analyses. Such study types can suggest hypotheses but typically need more detailed peer-reviewed reporting to confirm applicability.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Publicationrttnews.com
AuthorsRTTNews Staff Writer
Indexed viaBing News
Source typeWeb article
PublishedOct 11, 2026, 1:37 PM
Content availableFull source text

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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