Cure8 news brief
Cure8 news brief
Conference analyses describe how subcutaneous infliximab performs after stopping IV treatment and when compared with IV infliximab for ileal/ileocolonic Crohn's — information that could affect treatment decisions for patients and clinicians.
Patients on or considering infliximab (including those switching from IV to subcutaneous), gastroenterologists and IBD clinicians, and researchers studying biologic formulations and biomarkers in IBD.
Celltrion will present two new analyses at ACG 2026: a post-hoc look at patients who restarted subcutaneous infliximab after an interruption in intravenous therapy, and a pooled, propensity-matched comparison of subcutaneous versus intravenous infliximab in ileal/ileocolonic Crohn's disease.
The interruption analysis evaluated prior anti-drug antibody status, timing between last IV dose and restart of subcutaneous therapy, and tracked clinical response, serum drug levels, fecal calprotectin, and CRP over time.
The pooled Crohn's analysis compared clinical remission and endoscopic outcomes at Week 54 between matched groups receiving subcutaneous versus IV infliximab.
Presentations are analyses to be delivered at ACG 2026; they appear to be post-hoc and pooled/propensity-matched analyses. Such study types can suggest hypotheses but typically need more detailed peer-reviewed reporting to confirm applicability.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.