Journal of drugs in dermatology : JDD
Cure8 research brief
Why This Matters
Because PG is linked to IBD and can be triggered by surgery, a perioperative immunosuppressive approach reported here may be relevant to patients with IBD who have had prior PG or are planning reconstructive surgery.
Who Should Pay Attention
Patients with IBD (Crohn’s disease or ulcerative colitis) who have a history of pyoderma gangrenosum or are facing surgery; surgeons and IBD clinicians involved in perioperative care.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This is a single-case report, not a clinical trial. The authors describe that PG developed after previous surgeries and that giving immunosuppressive therapy (cyclosporine combined with prednisone) before and after the third surgery was associated with no recurrence in this patient.
The report illustrates a perioperative strategy clinicians sometimes use to reduce the risk of postoperative PG in patients with a prior history — starting immunosuppression around the time of surgery. The paper focuses on one patient’s course and treatment choices rather than providing comparative data or standardized protocols.
If you have IBD and a history of PG or prior postoperative PG, discuss risks and perioperative immunosuppression planning with your surgical and IBD care teams; this report does not establish safety or efficacy beyond this case.
Keep In Mind
This article is a single-case report (abstract-level content supplied). It describes one patient’s experience and perioperative management; it does not provide controlled evidence, and individual risks, benefits, and monitoring needs must be assessed by clinicians.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationJournal of drugs in dermatology : JDD
AuthorsLi LS, Lau WC, Lebwohl M
Study typeIm, journal article, case reports
Indexed viaEurope PMC
Source typeResearch paper
PublishedSep 1, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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