Cure8

Why This Matters

A dietary protein from donkey milk showed anti-inflammatory, antioxidant, and microbiome effects in a mouse model of colitis, which could point to new functional-food approaches worth further study for ulcerative colitis prevention or adjunctive care.

Who Should Pay Attention

Researchers, clinicians, and patients interested in diet/microbiome interventions for ulcerative colitis or IBD.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

This mouse study tested donkey whey protein (DWP) in a common chemical colitis model (3% DSS) and found that higher-dose DWP (2.0 g/kg) was associated with less weight loss, improved colon tissue appearance, lower pro-inflammatory cytokine IL-6, higher antioxidant markers (GSH, GSH-Px), and shifts in gut bacteria toward several genera seen in healthy controls.

The report interprets these findings as DWP helping to preserve the mucosal barrier, modulate immune responses, reduce inflammation, and improve antioxidant capacity in DSS-induced colitis. The authors suggest DWP could be explored as a natural functional ingredient for adjunctive prevention or treatment of ulcerative colitis.

This summary is based on the article abstract provided by the journal; Cure8 has not reviewed the full paper beyond the supplied text.

Keep In Mind

Findings come from a controlled DSS-induced colitis experiment in mice and are described in the article abstract; they are preliminary and not evidence that DWP works in humans.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationJournal of Functional Foods
AuthorsZongjie Ma, Shiqi Meng, Chunyun Yin +4 more
InstitutionLiaocheng University
Study typeArticle
Indexed viaOpenAlex
Source typeResearch paper
PublishedOct 31, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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