Journal of the Science of Food and Agriculture
Cure8 research brief
Why This Matters
The study suggests that a soluble fiber from foxtail millet can lessen colitis in a mouse model by changing gut fungal communities and improving barrier proteins — pointing to a possible food‑based approach worth further study.
Who Should Pay Attention
Researchers (microbiome/mycobiome, preclinical IBD), clinicians interested in diet–microbiome treatments, and patients curious about functional foods for gut health.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This study (abstract) reports that a soluble dietary fiber extracted from foxtail millet bran (FMB‑SDF) reduced signs of chronic colitis in a DSS mouse model and altered the gut fungal community.
The investigators also used fecal microbiota transplantation (FMT) to show the protective effect was microbiota‑mediated and observed changes in colonic markers including reduced Ki‑67 expression and increased tight junction protein ZO‑1. The work is preclinical: it used C57BL/6J mice with DSS‑induced chronic colitis, not human patients.
The paper highlights fungi (mycobiome) as the target of modulation and suggests FMB‑SDF as a potential functional food candidate rather than an approved treatment. If you read the full paper, expect detailed methods on the fiber preparation, dosing in mice, fungal community sequencing, and FMT experiments.
This abstract alone does not provide information about safety or efficacy in humans.
Keep In Mind
Findings are from a DSS mouse model and an abstract‑level article; human safety and efficacy are not established.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationJournal of the Science of Food and Agriculture
PublisherWiley
AuthorsRuipeng Yang, Jieya Yang, Zihua Su +5 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedSep 20, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
Structural Characteristics and Efficacy of Polysaccharides from Fenjiu Vinasse in Alleviating DSS-Induced Ulcerative Colitis
The study identifies a specific polysaccharide fraction (VPS-30) that reduced inflammation and improved gut barrier markers in cell and mouse models of colitis, suggesting a possible new functional-food lead for...
The protein extracted from fermented Zanthoxylum bungeanum seeds mitigates DSS-induced ulcerative colitis by orchestrating inflammatory cytokine modulation, counteracting oxidative stress, and safeguarding gut microbiota homeostasis.
The study suggests a fermented seed protein ingredient may reduce inflammation, oxidative stress, and microbiota imbalance in an experimental colitis model — mechanisms relevant to IBD. That could inform future dietary...
Extracts of Chrysanthemum morifolium Ramat. alleviated colitis-induced cognitive dysfunction through the BDNF/TrkB/CREB signaling pathway
IBD can cause cognitive and neurological symptoms. This preclinical study suggests a flavonoid-rich Chrysanthemum extract reduced colitis and related cognitive deficits in mice by changing the gut microbiota and...