DEN Open
Cure8 research brief
Why This Matters
Recurrent delayed bleeding after endoscopic stricturotomy is a serious complication that can lead to repeat procedures or surgery; this case suggests covering the ES wound with polyglycolic acid (PGA) sheet plus fibrin glue stopped recurrent bleeding and avoided abdominal surgery in one patient with Crohn’s disease.
Who Should Pay Attention
Endoscopists, gastroenterologists, colorectal surgeons, and Crohn’s patients facing post‑anastomotic strictures or repeated post‑endoscopic bleeding.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This abstract reports a case where repeated delayed bleeding after endoscopic stricturotomy (ES) for an ileo‑sigmoid anastomotic stricture in Crohn’s disease was ultimately controlled by covering the wound with polyglycolic acid (PGA) sheets plus fibrin glue.
Before PGA coverage the team attempted multiple endoscopic hemostatic measures (soft coagulation with vascular forceps, synthetic peptide gel, clips) and an infliximab infusion without durable control; the PGA sheet prevented further rebleeding and allowed avoidance of surgery.
The report is an abstract-level case description (single patient) published in DEN Open; it suggests PGA sheet/fibrin glue wound coverage may be a useful rescue option after recurrent post‑ES bleeding but does not establish effectiveness beyond this case.
Keep In Mind
Single‑patient case report presented as an abstract in DEN Open; not evidence of general efficacy. Details and outcomes beyond the abstract were not available in the provided text.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationDEN Open
AuthorsHidezumi Kikuchi, Taka Asari, Tetsuya Tatsuta +7 more
InstitutionHirosaki University Hospital
Study typeArticle
Indexed viaOpenAlex
Source typeResearch paper
PublishedAug 27, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Cure8 could only read part of this source from PubMed Central, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Infliximab, and Azathioprine.