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Transient Right Temporal Visual Field Loss Temporally Associated with Maintenance Infliximab in Crohn's Disease: A Case Report with Focused Literature Review.
Case reports in gastroenterology

Cure8 research brief

Transient Right Temporal Visual Field Loss Temporally Associated with Maintenance Infliximab in Crohn's Disease: A Case Report with Focused Literature Review.

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Complications Infliximab Anti-TNF Imaging Pain Case Report Adult patients Clinicians

Why This Matters

The report highlights a rare transient neuro-ophthalmic event occurring shortly after infliximab infusion, which may be important for patients and clinicians using anti-TNF therapy to recognize and evaluate.

Who Should Pay Attention

Adult patients on infliximab/anti-TNF therapy, clinicians prescribing biologics, and caregivers monitoring for neurological or visual symptoms.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

A 32-year-old man in remission on infliximab experienced sudden right temporal visual field loss lasting 15–30 minutes, followed by several hours of blurred vision, mild periorbital pain, and headache about 2 days after an infusion.

Eye exam, brain and orbit MRI/CT with contrast, ECG, and transthoracic echocardiography were unremarkable; symptoms resolved spontaneously. The patient reported a prior transient right-sided limb weakness after earlier infliximab exposure, suggesting a recurrent transient neurological pattern.

The authors emphasize that a single case cannot establish causality. They recommend excluding vascular, inflammatory, demyelinating, and migrainous causes when similar events occur and remaining vigilant for rare transient neurological symptoms in patients receiving anti-TNF agents.

Keep In Mind

Single-case (case report) evidence cannot establish causation. The published content is an abstract-level report; interpretation should be cautious and consider broader safety data and clinician evaluation for alternate causes.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationCase reports in gastroenterology
AuthorsShahbaz A, AlMohtasib S, Sajjadi F +2 more
Study typeJournal article, case reports
Indexed viaEurope PMC
Source typeResearch paper
PublishedJan 1, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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