Respirology case reports
Cure8 research brief
Why This Matters
This matters because it documents organising pneumonia occurring during biomarker-confirmed UC remission and emphasizes that lung disease in IBD patients may be disease-intrinsic rather than always drug-induced. Expert pathology review and exclusion of medication causes changed treatment for this patient.
Who Should Pay Attention
Adult patients with ulcerative colitis, gastroenterologists, pulmonologists, and clinicians managing extraintestinal manifestations; researchers interested in gut–lung immune interactions.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This report describes a 76‑year‑old woman with longstanding pancolonic ulcerative colitis who developed organising pneumonia while her gut disease was in biomarker-confirmed remission on stable mesalamine.
The authors say drug-induced lung disease was carefully excluded, pathology review changed the biopsy diagnosis (from fibrotic NSIP to organising pneumonia), and the patient responded to corticosteroids — highlighting how lung biopsy interpretation can alter treatment.
The case also notes an atypical bronchoalveolar lavage neutrophil predominance (42% neutrophils) and discusses the possibility of gut–lung immune interactions in UC-associated organising pneumonia. The authors place the case in the context of the 2025 ERS/ATS classification that now lists UC as a secondary cause of cicatricial organising pneumonia.
Clinical takeaways: organising pneumonia can occur as a disease-intrinsic extraintestinal complication of ulcerative colitis even during biomarker-confirmed remission; systematic exclusion of drug causes and expert pathology review influenced management in this case.
Keep In Mind
This is a single case report (abstract-level content provided). It illustrates diagnostic and management challenges but does not provide generalizable risk estimates or treatment guidelines. The report uses faecal calprotectin to document colonic remission and notes pathology diagnostic discordance; treat interpretations accordingly.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationRespirology case reports
AuthorsJereisat RA, Ibrahim N, Dahdel M
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedSep 8, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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