Cure8

Why This Matters

Anastomotic strictures after TPC–IPAA can impair bowel function and quality of life; identifying preoperative pelvic and body-composition risk factors could help tailor surgical planning or follow-up.

Who Should Pay Attention

post-surgery-patients, clinicians, researchers, adult-patients

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

This paper reports a retrospective cohort study of 55 ulcerative colitis patients who underwent total proctocolectomy with ileal pouch–anal anastomosis (TPC–IPAA).

The authors measured pelvic dimensions and body-composition metrics on preoperative CT and examined associations with severe anastomotic stricture (defined as requiring endoscopic balloon dilatation within 1 year). They found that a smaller composite pelvic size (pelvic index) was associated with higher odds of severe anastomotic stricture after TPC–IPAA.

Higher skeletal muscle index and greater visceral fat were also associated in univariable analyses, but only the pelvic index remained significant in multivariable modeling; the muscle finding was borderline.

These results suggest preoperative pelvic anatomy and body composition might help identify patients at higher risk for pouch anastomotic strictures, which could inform surgical planning or closer postoperative surveillance.

Keep In Mind

Findings are from a retrospective cohort and labeled as exploratory; sample size is small and results need validation in larger prospective studies.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationBMC Surgery
PublisherSpringer Science and Business Media LLC
AuthorsMasatsugu Kojima, Toru Miyake, Shigeki Bamba +10 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedOct 7, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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