ClinicalTrials.gov
Cure8 trial brief
Why This Matters
Perianal fistulas are a common, often debilitating complication of Crohn's disease that require accurate imaging to guide medical and surgical care. If TPUS performs well, it could offer a faster, lower-cost, outpatient-friendly option compared with MRI or EUA.
Who Should Pay Attention
Adults with Crohn's disease or suspected perianal fistulas; colorectal surgeons, gastroenterologists, and radiologists; researchers studying fistula imaging or access to diagnostic care.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment50 participants
Study statusRecruiting
Source depthTrial registry record
What To Know
This is a prospective, single-center diagnostic accuracy trial where each enrolled adult will receive TPUS, MRI, EUS, and EUA within 10 days. Imaging reads are performed independently and blinded. EUA is treated as the gold standard, and EUS is used as a reference standard in comparisons.
The study uses routine clinical imaging performed by experienced operators; no experimental treatments are given. Key outcomes include per-lesion sensitivity for TPUS versus MRI, detection of internal openings and abscesses, classification accuracy (Parks and AGA), and whether imaging findings change clinical management.
Keep In Mind
This entry is a trial record (prospective diagnostic accuracy study) and does not present results. Interpretive conclusions should await published study findings.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorAsian Institute of Gastroenterology, India
Trial IDNCT07794410
Study typeInterventional
Trial phaseNA
Enrollment50 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedAug 31, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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