ClinicalTrials.gov
Cure8 trial brief
Why This Matters
The study aims to clarify differences in visceral sensitivity and collect multiple biological samples that could help explain why some people with IBD have IBS-like symptoms. Findings could inform better symptom-targeted treatments in the future.
Who Should Pay Attention
Adults with IBS, people with active or remitted Crohn's disease or ulcerative colitis (with or without IBS symptoms), clinicians who manage IBD/IBS, and researchers studying gut sensitivity, gut–brain interactions, or biomarkers.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment99,999,999 participants
Study statusRecruiting
Source depthTrial registry record
What To Know
The study collects rectal and colon biopsies, blood, nasal mucosa samples, stool, questionnaires, colon transit measurements, and brain MRI scans. The main measurable outcome is visceral sensitivity measured by a rectal barostat performed at the time of investigation.
If you consider participating: eligibility is 18–65 years and requires stopping medications that affect GI motility or perception at least 24 hours before study procedures. The study is based at University Hospitals Leuven (Belgium) and is listed as recruiting on ClinicalTrials.gov.
No results are reported in this record; this entry describes the study design and planned measurements.
Keep In Mind
This is a registered interventional trial record describing planned measurements and sample collection; no study results or outcomes are reported here. Participation requires stopping certain medications briefly and meeting inclusion/exclusion criteria. The ClinicalTrials.gov entry should be consulted for updated recruitment status and contact details.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorKU Leuven
Trial IDNCT02421705
Study typeInterventional
Trial phaseNA
Enrollment99,999,999 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedOct 22, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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