Cure8 news brief
Many people with Crohn’s disease have ongoing inflammation despite stable medication. If dietary personalization can reduce inflammation, it could offer a nonpharmacologic add-on to help bridge gaps without immediate medication changes.
Adults with Crohn’s disease who have persistent inflammation despite stable treatment; clinicians managing IBD; researchers interested in diet–microbiome–genetics interactions; patients interested in nutrition-based therapies.
A University of Miami team led by Dr. Oriana Damas is launching a randomized 16-week trial (122 adults) testing a personalized, catered anti-inflammatory diet vs. participants’ usual foods (with reduced exposure to pesticides/preservatives) as an add-on to stable medical therapy for people with mild–moderate Crohn’s disease and ongoing inflammation.
Researchers will measure blood and stool inflammatory markers, intestinal ultrasound, and analyze the gut microbiome and genetics to see who responds.
The study treats diet as an adjunct, not a replacement for biologics or other advanced medications, and the catered menus emphasize fiber, a low omega-6:omega-3 ratio, and avoidance of ultra-processed foods while being tailored to cultural and personal preferences. This work is funded in part by a U.S.
Department of Defense grant and aims to develop precision nutrition approaches that integrate microbiome and genetic data. The article describes study design, goals, and measures but does not report results.
This is a trial protocol/launch article describing planned research rather than results. The study enrolls patients who have not recently changed medications so findings will apply to adjunctive diet effects. outcomes are pending and the article does not provide effectiveness data.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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