iScience
Cure8 research brief
Cardiac structure and function in patients with inflammatory bowel disease.
Complications
Systematic Review or Meta Analysis
Adult patients
Clinicians
Researchers
Inflammatory bowel disease
Why This Matters
A pooled analysis found modest differences in cardiac structure and function in people with IBD versus controls, which may relate to the higher cardiovascular risk seen in this population.
Who Should Pay Attention
Adult patients with IBD, clinicians (gastroenterologists, primary care), and researchers focused on cardiovascular risk in inflammatory diseases.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This paper reports modest but consistent differences between people with IBD and healthy controls in several cardiac measures: slightly thicker ventricular walls, lower ejection fraction, and reduced (less negative) global longitudinal strain. The analysis pooled 28 studies with over 1,600 IBD patients and about 1,300 controls.
Measures varied across studies and subgroup analyses suggested differences related to disease activity, age at onset, and IBD subtype. The authors conclude that standardized prospective cardiac studies are needed to better define cardiovascular assessment and risk stratification in IBD.
Keep In Mind
This entry summarizes the article abstract (systematic review and meta-analysis). The authors emphasize cautious interpretation of individual parameter results and call for standardized prospective studies to clarify cardiac assessment and risk stratification in IBD.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationiScience
AuthorsYang Y, Luo X, Zhou L +4 more
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedJun 27, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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