Journal of pediatric gastroenterology and nutrition
Cure8 research brief
Why This Matters
Children diagnosed with IBD can develop other immune-related diseases, growth and weight problems, skin conditions, and serious infections over time. Knowing the frequency and risk factors helps families and clinicians watch for these issues and consider them in long-term care planning.
Who Should Pay Attention
Pediatric patients with IBD, parents and caregivers, pediatric gastroenterologists and other clinicians managing young people with IBD, and researchers studying comorbidities and long-term outcomes in paediatric-onset IBD.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This study used a well-established regional registry (EPIMAD) to follow 1,344 children diagnosed with IBD between 1988–2011 and tracked multiple chronic conditions through 2013.
About 16% developed at least one extraintestinal manifestation and roughly 9% developed another immune-mediated inflammatory disease; dermatologic conditions and serious infections were also reported. Underweight affected a sizable proportion (about 18%) while obesity was seen in about 8% of the cohort.
Younger age at diagnosis and more extensive disease were linked to higher risk of EIMs and underweight; Crohn’s disease had a stronger association with underweight. Clinical context: Patients who developed dermatologic conditions or other IMIDs were more likely to receive biologic therapies during follow-up.
The authors also observed increasing incidence over calendar time of obesity, IMIDs, and dermatologic conditions in this cohort.
Keep In Mind
This classification and note are grounded in the article abstract (structured content depth: abstract). The study is retrospective, population-based, and follows patients diagnosed between 1988–2011 with follow-up to 2013; temporal trends and associations reported reflect that timeframe and registry data.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationJournal of pediatric gastroenterology and nutrition
AuthorsNicolas Richard, Ariane Leroyer, Hélène Sarter +10 more
InstitutionDepartment of Gastroenterology, Univ Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, "Nutrition, Inflammation and Microbiota-Gut-Brain Axis", CHU Rouen, Rouen, France.
Study typeJournal article
Indexed viaPubMed
Source typeResearch paper
PublishedOct 14, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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