Cure8

Why This Matters

This study suggests that older-onset IBD is managed more conservatively and experiences fewer extraintestinal manifestations. Patients and clinicians should be aware that age can influence treatment choices and that age-specific guidance may be needed.

Who Should Pay Attention

Older adult IBD patients and their caregivers, gastroenterologists and IBD clinicians, and researchers studying age-related differences in IBD management.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

This is a single retrospective cohort study of 1,245 adult IBD patients (56 with disease onset at ≥60 years) comparing demographics, disease features, and treatment patterns between older- and younger-onset groups.

Key findings reported in the abstract: older-onset disease was more often ulcerative colitis, had fewer extraintestinal manifestations, and used immunosuppressive and biologic therapies less frequently.

Clinical context The study highlights potential undertreatment of older-onset IBD due to safety concerns, and the authors call for research and guidelines tailored to older patients to balance risks and long-term outcomes.

Keep In Mind

This report is a retrospective cohort from a single center/time span (1993–2023) summarized in the article abstract. Findings describe treatment patterns and associations but do not establish causality; individual treatment decisions consider comorbidities and risks not detailed here.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationWorld Journal of Gastroenterology
PublisherBaishideng Publishing Group Inc.
AuthorsFatih Kivrakoglu, Vedat Kilic, Mustafa Ergin +3 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedJul 21, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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