Cure8 research brief
The study links socioeconomic status to long-term risk of IBD and shows that healthier lifestyles explain only part of the protective effect of higher SES. That suggests social factors beyond individual lifestyle may influence who develops IBD.
Researchers, clinicians, policy researchers focused on social determinants of health, and adult patients interested in prevention or risk factors for IBD.
The study followed 374,507 adults without IBD for a median of ~14.6 years and identified 2,381 incident IBD cases. Participants were grouped into low, medium, and high SES patterns; high SES had roughly a 45% lower adjusted risk of IBD compared with low SES. Higher education showed the strongest individual association.
The combination of high SES and a healthy lifestyle was associated with the lowest risk. Mediation analysis estimated that measured lifestyle factors accounted for a minority of the SES effect, meaning other factors tied to socioeconomic position likely contribute.
Observational design limits causal claims; mediation results depend on measured mediators and analytic assumptions. The provided content is an abstract-level summary from the journal.
Review the original publication for the complete reporting, methods, and context.
Conflict statement: Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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