Case reports in medicine
Cure8 research brief
Why This Matters
KTS can mimic ulcerative colitis with bloody diarrhea and colonic vascular lesions, so awareness may prevent misdiagnosis and guide appropriate multidisciplinary care. Early recognition can help address bleeding, anemia, and nutrition issues.
Who Should Pay Attention
Adults with unexplained or atypical IBD-like symptoms, gastroenterologists, vascular anomaly specialists, and multidisciplinary care teams.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This case report describes a 64-year-old man with Klippel-Trénaunay syndrome (KTS) whose gastrointestinal vascular malformations produced foul-smelling bloody diarrhea and extensive colonic varicosities that had been misdiagnosed previously as ulcerative colitis.
Workup showed severe iron-deficiency anemia, splenomegaly, fundal varices, and a continuous 15-cm area of colonic involvement from the anal verge with varicosities and bleeding, leading clinicians to diagnose KTS-related GI disease.
The authors highlight that diarrhea is an uncommon but possible manifestation of GI involvement in KTS and may reflect vascular and lymphatic malformations causing protein-losing enteropathy and bleeding.
They emphasize the diagnostic challenge because KTS can mimic inflammatory bowel disease (IBD) and encourage multidisciplinary evaluation to manage symptoms and prevent complications. This summary is based on the article abstract provided in PubMed (structured content depth: abstract); Cure8 did not review additional outside materials.
Keep In Mind
Single case report from a PubMed abstract; findings are illustrative but not generalizable. The brief is grounded in the article abstract and not a full systematic review.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationCase reports in medicine
AuthorsModar AlAli, Tarek Khazem, Hatem Yousef Almohamad +2 more
InstitutionFaculty of Medicine, Damascus University, Damascus, Syria, damascusuniversity.edu.sy.
Study typeJournal article
Indexed viaPubMed
Source typeResearch paper
PublishedJul 21, 2026, 12:00 AM
Content availableJournal abstract
Conflict statement: The authors declare no conflicts of interest.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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