Inflammatory Bowel Diseases
Cure8 research brief
Why This Matters
CMV can complicate acute colitis in people with IBD and may change treatment decisions; knowing which tests are most sensitive or specific helps clinicians decide how to work up suspected CMV colitis during hospitalizations.
Who Should Pay Attention
Clinicians caring for hospitalized IBD patients with acute colitis, researchers studying CMV diagnostics in IBD, and patients with moderate–severe IBD who are immunosuppressed or hospitalized for colitis.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
The review suggests tissue PCR is very sensitive for CMV colitis but less specific, while stool and serum PCR and pp65 antigenemia/H&E may help confirm disease when positive. Clinicians and researchers should interpret PCR results alongside clinical context and immunosuppression status.
The article is an abstract-based systematic review and meta-analysis published in Inflammatory Bowel Diseases; Cure8’s brief is grounded in the article abstract provided by the journal.
Keep In Mind
This classification and brief are grounded in the article abstract (structured content depth: abstract). The study pooled published data up to March 2025 but further research—especially to define PCR thresholds and validate stool PCR—is needed before changing practice.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationInflammatory Bowel Diseases
PublisherOxford University Press (OUP)
AuthorsSimon Mark Seddon, David Godfrey, Sheng Wei Lo +4 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedJul 15, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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