Case reports in medicine
Cure8 research brief
Why This Matters
This report shows that vascular malformations from Klippel-Trénaunay syndrome can mimic ulcerative colitis with bloody diarrhea and extensive colonic involvement, so some people labeled with IBD might have an alternative vascular cause requiring different evaluation.
Who Should Pay Attention
Patients with atypical or treatment-refractory IBD symptoms, gastroenterologists, vascular specialists, and clinicians evaluating GI bleeding.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This case report describes a 64-year-old man whose gastrointestinal Klippel-Trénaunay syndrome (KTS) produced recurrent bloody, foul-smelling diarrhea and extensive colonic varicosities that had been misdiagnosed previously as ulcerative colitis.
The authors suggest diarrhea in KTS may stem from vascular and lymphatic malformations and could cause protein-losing enteropathy and iron-deficiency anemia. Because this is a single case report, it illustrates a possible IBD mimic rather than proving frequency or typical outcomes.
For anyone with atypical features of IBD—such as limb hypertrophy, varicosities, or refractory bleeding—multidisciplinary evaluation and vascular-focused imaging may be helpful.
Keep In Mind
Single-patient case report (abstract-level). Findings illustrate a diagnostic mimic and do not establish how commonly KTS causes diarrhea or how it should be treated generally.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationCase reports in medicine
AuthorsAlAli M, Khazem T, Almohamad HY +2 more
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedJul 21, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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