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Severe malnutrition and persistent myopenia despite weight recovery in newly diagnosed stricturing Crohn's disease: A case report.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

Cure8 research brief

Severe malnutrition and persistent myopenia despite weight recovery in newly diagnosed stricturing Crohn's disease: A case report.

1 min read
Complications Infliximab Azathioprine Steroids Anti-TNF Immunomodulators Weight Loss Nausea

Why This Matters

Muscle loss (myopenia) can persist in Crohn's disease even after weight recovery and clinical remission, which may affect long-term outcomes. Identifying persistent muscle depletion with body composition measures could prompt earlier nutritional and rehabilitative interventions.

Who Should Pay Attention

Patients with Crohn's disease (newly diagnosed or with significant weight loss), gastroenterologists, dietitians, and IBD care teams

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

The report highlights that body weight and clinical remission may not reflect recovery of skeletal muscle. Computed tomography–based body composition analysis and bioelectrical measures identified ongoing myopenia despite ~25% weight regain, increased adipose tissue, and improved dietary intake.

The authors suggest early nutritional assessment and longitudinal body composition monitoring to detect and address persistent muscle depletion.

Keep In Mind

This classification and note are based on the article abstract (case report) from Nutrition in Clinical Practice. As a single-patient report, it illustrates an issue but cannot determine how common this is or the best corrective strategies.

Source Details

Review the original publication for the complete reporting, methods, and context.

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Research paper Evidence type derived from source or registry metadata.
PublicationNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
AuthorsBeatriz Gabriela da Costa, Jeniffer Naomy Nobre, Ryan Nunes Yoshio Yoshihara +8 more
InstitutionDepartment of Internal Medicine, Medical School, São Paulo State University (Unesp), Botucatu, São Paulo, Brazil.
Study typeJournal article
Indexed viaPubMed
Source typeResearch paper
PublishedOct 14, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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