Cure8 research brief
Non-invasive biomarkers can help detect and monitor IBD activity, distinguish IBD from other GI conditions, and potentially predict relapse—tools that may reduce need for invasive tests.
This review identifies several promising neutrophil-derived markers beyond calprotectin that could improve testing options for people with IBD, including children.
Clinicians managing IBD, researchers studying biomarkers and diagnostics, and patients (including pediatric patients) interested in non-invasive monitoring options.
This review summarizes evidence on four neutrophil-derived proteins (myeloperoxidase, S100A12, lactoferrin, lipocalin) as non-invasive biomarkers for IBD, including fecal and serum testing and potential rapid tests.
It highlights S100A12’s strong discrimination between IBD and other conditions (noting better performance in children), lactoferrin’s similarity to calprotectin, and growing interest in lipocalin and myeloperoxidase.
This article is a journal review (abstract-level summary provided). Findings summarize existing studies; they do not represent a single new clinical trial. Further validation studies and clinical implementation work are needed before changing standard practice.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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