Cure8 news brief
Smoking is a known risk factor for Crohn’s recurrence after bowel surgery. This study suggests newer products marketed as potentially safer (HNBT and e-cigarettes) were also linked to higher postoperative endoscopic recurrence compared with nonsmoking.
Adults with Crohn's disease who are current or former smokers, patients planning or recovering from bowel resection, colorectal surgeons, and gastroenterologists.
This news item summarizes a multi-center retrospective study comparing postoperative endoscopic recurrence rates after ileocolic resection among nonsmokers, traditional cigarette smokers, heat-not-burn tobacco (HNBT) users, and e-cigarette users.
The study included 937 patients across centers in Italy, Spain, and France and found higher recurrence rates in all smoking groups versus nonsmokers (traditional cigarettes ~69.4%, HNBT ~63.9%, e-cigarettes ~60.6% vs nonsmokers ~40.8%). The authors recommend managing HNBT and e-cigarette users similarly to traditional smokers in the postoperative setting.
The report cites Parigi et al., Am J Gastroenterol 2026;121(8):1954-1962 (doi: 10.14309/ajg.0000000000003810). This brief is based on the article's summary of that retrospective clinical study; Cure8 has not independently reviewed the full published paper.
This was a retrospective observational study, which can show association but not prove causation. Patients using multiple nicotine products were excluded. The brief is grounded in the and references the published paper for full details.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
Postoperative endoscopic recurrence after ileocolic resection is an important risk for people with Crohn’s disease; this study links HNBT and possibly e-cigarette use to higher recurrence rates, which could affect...
This study suggests heated-tobacco products (and possibly e-cigarettes) may increase the risk of endoscopic recurrence after ileocolic resection for Crohn’s disease, which could affect postoperative outcomes and...
The study highlights factors linked to needing another operation after ileocecal resection for Crohn’s disease and suggests postoperative biologic therapy may lower long-term reoperation risk. That directly affects...
